Gene: AT1G70940 (Arabidopsis thaliana)

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Gene Identifier
Transcript Identifier
Gene Type
Coding gene
1 : 26743170-26745871 : positive


Gene family
(172 genes in 14 species)
specific family
Duplication type
Block duplicate

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Auxin efflux carrier family protein
Curated Summary
A regulator of auxin efflux and involved in differential growth. PIN3 is expressed in gravity-sensing tissues, with PIN3 protein accumulating predominantly at the lateral cell surface. PIN3 localizes to the plasma membrane and to vesicles. In roots, PIN3 is expressed without pronounced polarity in tiers two and three of the columella cells, at the basal side of vascular cells, and to the lateral side of pericycle cells of the elongation zone. PIN3 overexpression inhibits root cell growth. Protein phosphorylation plays a role in regulating PIN3 trafficking to the plasma membrane.
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Identifier Name





Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009926IMP, ISSRCA, UniProtauxin polar transport1 2 3 4 5 6 7 8
GO:0009606IMPGene Ontologytropism1
GO:0007389IGI, RCA, UniProtpattern specification process1 2 3 4 5 6 7
GO:0010082IGIUniProtregulation of root meristem growth1 2 3 4 5 6
GO:0048364IGI, IMPGene Ontologyroot development1 2
GO:0009630TASGene Ontologygravitropism1
GO:0048766IMPUniProtroot hair initiation1 2 3 4 5 6
GO:0048767IMP, RCA, UniProtroot hair elongation1 2 3 4 5 6 7
GO:0009416IDAUniProtresponse to light stimulus1 2 3 4 5 6
GO:0009958IMPUniProtpositive gravitropism1 2 3 4 5 6
GO:0010315IMPUniProtauxin efflux1 2 3 4 5 6
GO:0000271RCAGene Ontologypolysaccharide biosynthetic process1
GO:0008356RCAGene Ontologyasymmetric cell division1
GO:0008361RCAGene Ontologyregulation of cell size1
GO:0009825RCAGene Ontologymultidimensional cell growth1
GO:0009932RCAGene Ontologycell tip growth1
GO:0010015RCAGene Ontologyroot morphogenesis1
GO:0010218RCAGene Ontologyresponse to far red light1
GO:0010817RCAGene Ontologyregulation of hormone levels1
GO:0040007RCAGene Ontologygrowth1
GO:0043481RCAGene Ontologyanthocyanin accumulation in tissues in response to UV light1
GO:0048765RCAGene Ontologyroot hair cell differentiation1
GO:0071555RCAGene Ontologycell wall organization1
GO:0055085IEAUniProttransmembrane transport1 2 3 4 5

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005215ISSGene Ontologytransporter activity1
GO:0009672ISSGene Ontologyauxin:hydrogen symporter activity1
GO:0010329ISOPLAZA Integrative Orthologyauxin efflux transmembrane transporter activitySL05G008060 SL04G007690

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886IDAGene Ontologyplasma membrane1
GO:0012506IDAUniProtvesicle membrane1 2 3 4 5 6
GO:0016328IDAUniProtlateral plasma membrane1 2 3 4 5 6
GO:0009986IDAUniProtcell surface1 2 3 4 5 6
GO:0016021IEAUniProtintegral to membrane1 2 3 4 5

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR014024Auxin efflux carrier, plant type
IPR004776Auxin efflux carrier

Mapman id Description
17.2.2hormone metabolism.auxin.signal transduction
No SignalP domains detected for this gene.