Gene: AT1G65060 (Arabidopsis thaliana)

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Gene Identifier
AT1G65060
Transcript Identifier
AT1G65060.1
Gene Type
Coding gene
Location
1 : 24167385-24171457 : negative

Family

Gene family
HOM03M000192
(259 genes in 14 species)
specific family

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Descriptions

Description
4-coumarate:CoA ligase 3
Curated Summary
encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. mRNA levels are not induced in response to wounding or to fungal infection by P. parasitica. mRNA is expressed in flowers, to a lesser degree in mature leaves and siliques and marginally in seedling roots and bolting stems of mature plants. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, cinnamic acid and 5-OH-ferulic acid. At4CL3 was unable to use sinapic acid as substrate.
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Identifiers

Identifier Name
alias4-coumarate:CoA ligase 3
alias4CL3
uniprotQ9S777

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0010584IMPUniProtpollen exine formation1 2 3 4 5 6
GO:0009411IEPGene Ontologyresponse to UV1
GO:0009611IEPGene Ontologyresponse to wounding1
GO:0009698TASUniProtphenylpropanoid metabolic process1 2 3 4 5 6
GO:0050832IEPGene Ontologydefense response to fungus1
GO:0009718RCAGene Ontologyanthocyanin-containing compound biosynthetic process1
GO:0009744RCAGene Ontologyresponse to sucrose1
GO:0009813RCAGene Ontologyflavonoid biosynthetic process1
GO:0010224RCAGene Ontologyresponse to UV-B1
GO:0008152IEAInterPrometabolic process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016207IDAUniProt4-coumarate-CoA ligase activity1 2 3 4 5 6
GO:0005524IEAUniProtATP binding1 2 3 4 5
GO:0003824IEAInterProcatalytic activity

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000873AMP-dependent synthetase/ligase
IPR025110AMP-binding enzyme C-terminal domain
IPR020845AMP-binding, conserved site

Mapman id Description
16.2.1.3secondary metabolism.phenylpropanoids.lignin biosynthesis.4CL
No SignalP domains detected for this gene.