Gene: AT1G63440 (Arabidopsis thaliana)

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Gene Identifier
AT1G63440
Transcript Identifier
AT1G63440.1
Gene Type
Coding gene
Location
1 : 23527655-23531109 : positive

Family

Gene family
HOM03M000315
(179 genes in 16 species)
specific family

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Descriptions

Description
heavy metal atpase 5
Curated Summary
The Arabidopsis P-type ATPase HMA5 is involved in Cu detoxification. hma5 mutant plants exhibit Cu hypersensitivity, which is especially dramatic in roots where HMA5 is mostly expressed.
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Identifiers

Identifier Name
aliasHMA5
aliasheavy metal atpase 5
uniprotQ9SH30

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0010273IMPUniProtdetoxification of copper ion1 2 3
GO:0046688IMPGene Ontologyresponse to copper ion1
GO:0010043RCAGene Ontologyresponse to zinc ion1
GO:0006825IEAUniProtcopper ion transport1 2
GO:0006812IEAInterProcation transport
GO:0030001IEAInterPrometal ion transport

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0015662ISSGene OntologyATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism1
GO:0005524IEAUniProtATP binding1 2
GO:0019829IEAUniProtcation-transporting ATPase activity1 2
GO:0005507IEAUniProtcopper ion binding1 2
GO:0000166IEAInterPronucleotide binding
GO:0046872IEAInterPrometal ion binding
GO:0042626IEAPLAZA HomologyATPase activity, coupled to transmembrane movement of substancesHOM03M000315
GO:0042625IEAPLAZA HomologyATPase activity, coupled to transmembrane movement of ionsHOM03M000315
GO:1901265IEAPLAZA Homologynucleoside phosphate bindingHOM03M000315
GO:0016820IEAPLAZA Homologyhydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesHOM03M000315
GO:0015399IEAPLAZA Homologyprimary active transmembrane transporter activityHOM03M000315
GO:0015405IEAPLAZA HomologyP-P-bond-hydrolysis-driven transmembrane transporter activityHOM03M000315
GO:0043492IEAPLAZA HomologyATPase activity, coupled to movement of substancesHOM03M000315

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886ISMGene Ontologyplasma membrane1
GO:0016021IEAUniProtintegral to membrane1 2

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001757Cation-transporting P-type ATPase
IPR023214HAD-like domain
IPR018303P-type ATPase, phosphorylation site
IPR006121Heavy metal-associated domain, HMA
IPR006122Heavy metal-associated domain, copper ion-binding
IPR008250P-type ATPase, A domain
IPR027256Cation-transporting P-type ATPase, subfamily IB
IPR023299P-type ATPase, cytoplasmic domain N
IPR017969Heavy-metal-associated, conserved site

Mapman id Description
34.12transport.metal
No SignalP domains detected for this gene.