Gene: AT1G53000 (Arabidopsis thaliana)

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Gene Identifier
AT1G53000
Transcript Identifier
AT1G53000.1
Gene Type
Coding gene
Location
1 : 19745330-19747133 : negative

Family

Gene family
HOM03M004351
(22 genes in 15 species)
specific family

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Descriptions

Description
Nucleotide-diphospho-sugar transferases superfamily protein
Curated Summary
Encodes a mitochondrial-localized CMP-KDO (3-deoxy-D-manno-octulosonate) synthetase. This is the enzyme activating KDO as a nucleotide sugar prior to its incorporation into rhamnogalacturonan-II. Heterozygous mutants are defective in pollen development and in pollen tube elongation.
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Identifiers

Identifier Name
aliasCMP-KDO synthetase
aliasAtCKS
aliasKDSB
aliasCKS
uniprotQ9C920

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009103IEA, ISSUniProtlipopolysaccharide biosynthetic process1 2 3 4 5 6
GO:0009555IMPUniProtpollen development1 2 3 4 5 6
GO:0009860IMPUniProtpollen tube growth1 2 3 4 5 6
GO:0033468IDAUniProtCMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process1 2 3 4 5 6
GO:0019243RCAGene Ontologymethylglyoxal catabolic process to D-lactate1
GO:0008653IEAPLAZA Homologylipopolysaccharide metabolic processHOM03M004351

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016779ISSGene Ontologynucleotidyltransferase activity1
GO:0008690IDA, IEA, UniProt3-deoxy-manno-octulosonate cytidylyltransferase activity1 2 3 4 5 6

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005739IDAGene Ontologymitochondrion1
GO:0031307IDAUniProtintegral to mitochondrial outer membrane1 2 3 4 5 6
GO:0005737IEAInterProcytoplasm

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR0045283-deoxy-D-manno-octulosonate cytidylyltransferase
IPR003329Acylneuraminate cytidylyltransferase

Mapman id Description
10.1.12.4cell wall.precursor synthesis.KDO pathway.CMP-KDO Synthetase
No SignalP domains detected for this gene.