Gene: AT1G52500 (Arabidopsis thaliana)

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Gene Identifier
AT1G52500
Transcript Identifier
AT1G52500.2
Gene Type
Coding gene
Location
1 : 19560043-19562855 : positive

Family

Gene family
HOM03M003314
(27 genes in 16 species)
specific family

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Descriptions

Description
MUTM homolog-1
Curated Summary
Encodes one of the splice variants of Arabidopsis thaliana MutM homolog. Encodes a formamidopyrimidine-DNA glycosylase that has abasic lyase activity and is able to nick double- stranded oligonucleotides containing 8-oxo-7,8-dihydroguanine (8-oxoG) in vitro.
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Identifiers

Identifier Name
aliasA. THALIANA FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 1
aliasATMMH-1
aliasMUTM homolog
aliasFPG-1
aliasFORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 1
aliasFPG-2
aliasMMH-2
aliasFORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 2
aliasATFPG-1
aliasMUTM homolog-1
aliasMMH-1
aliasMMH
aliasATMMH-2
aliasATFPG-2
uniprotO80358

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006281IDA, IEA, UniProtDNA repair1 2 3 4 5 6
GO:0000741RCAGene Ontologykaryogamy1
GO:0006312RCAGene Ontologymitotic recombination1
GO:0009560RCAGene Ontologyembryo sac egg cell differentiation1
GO:0006979TASUniProtresponse to oxidative stress1 2 3 4 5 6
GO:0006284IEAUniProtbase-excision repair1 2 3 4 5
GO:0006289IEAUniProtnucleotide-excision repair1 2 3 4 5

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0019104IDA, ISS, UniProtDNA N-glycosylase activity1 2 3 4 5 6 7
GO:0003684IEAUniProtdamaged DNA binding1 2 3 4 5
GO:0008534IEAUniProtoxidized purine nucleobase lesion DNA N-glycosylase activity1 2 3 4 5
GO:0008270IEAUniProtzinc ion binding1 2 3 4 5
GO:0003906IEAInterProDNA-(apurinic or apyrimidinic site) lyase activity
GO:0003676IEAInterPronucleic acid binding
GO:0016799IEAInterProhydrolase activity, hydrolyzing N-glycosyl compounds
GO:0000702IEAPLAZA Homologyoxidized base lesion DNA N-glycosylase activityHOM03M003314

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IEA, ISMUniProtnucleus1 2 3 4 5 6

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR012319DNA glycosylase/AP lyase, catalytic domain
IPR000191DNA glycosylase/AP lyase
IPR010979Ribosomal protein S13-like, H2TH
IPR015886DNA glycosylase/AP lyase, H2TH DNA-binding

Mapman id Description
28.2DNA.repair
No SignalP domains detected for this gene.