Gene: AT1G51680 (Arabidopsis thaliana)

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Gene Identifier
AT1G51680
Transcript Identifier
AT1G51680.1
Gene Type
Coding gene
Location
1 : 19159007-19161464 : negative

Family

Gene family
HOM03M000192
(259 genes in 14 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
4-coumarate:CoA ligase 1
Curated Summary
encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. In addition to 4-coumarate, it also converts ferulate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, ferulic acid, caffeic acid and 5-OH-ferulic acid. At4CL1 was unable to use sinapic acid as substrate.
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Identifiers

Identifier Name
alias4-coumarate:CoA ligase 1
alias4-COUMARATE:COA LIGASE 1
aliasAT4CL1
aliasARABIDOPSIS THALIANA 4-COUMARATE:COA LIGASE 1
alias4CL.1
alias4CL1
uniprotQ42524

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009411IEPGene Ontologyresponse to UV1
GO:0009611IEP, RCAGene Ontologyresponse to wounding1 2
GO:0009620IEPGene Ontologyresponse to fungus1
GO:0009698TAS, RCAUniProtphenylpropanoid metabolic process1 2 3 4 5 6 7 8 9 10 11
GO:0006598RCAGene Ontologypolyamine catabolic process1
GO:0006612RCAGene Ontologyprotein targeting to membrane1
GO:0009805RCAGene Ontologycoumarin biosynthetic process1
GO:0009963RCAGene Ontologypositive regulation of flavonoid biosynthetic process1
GO:0010363RCAGene Ontologyregulation of plant-type hypersensitive response1
GO:0042398RCAGene Ontologycellular modified amino acid biosynthetic process1
GO:0008152IEAInterPrometabolic process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016207IDAUniProt4-coumarate-CoA ligase activity1 2 3 4 5 6 7 8 9 10
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7 8 9
GO:0003824IEAInterProcatalytic activity

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus1
GO:0005737IDAUniProtcytoplasm1 2 3 4 5 6 7 8 9 10

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000873AMP-dependent synthetase/ligase
IPR020845AMP-binding, conserved site
IPR025110AMP-binding enzyme C-terminal domain

Mapman id Description
16.2.1.3secondary metabolism.phenylpropanoids.lignin biosynthesis.4CL
No SignalP domains detected for this gene.