Gene: AT1G48410 (Arabidopsis thaliana)

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Gene Identifier
AT1G48410
Transcript Identifier
AT1G48410.2
Gene Type
Coding gene
Location
1 : 17886285-17891892 : negative

Family

Gene family
HOM03M000188
(260 genes in 15 species)
specific family

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Descriptions

Description
Stabilizer of iron transporter SufD / Polynucleotidyl transferase
Curated Summary
Encodes an RNA Slicer that selectively recruits microRNAs and siRNAs. There is currently no evidence that AGO1 Slicer is in a high molecular weight RNA-induced silencing complex (RISC). Mutants are defective in post-transcriptional gene silencing and have pleiotropic developmental and morphological defects. Through its action on the regulation of ARF17 expression, the protein regulates genes involved at the cross talk between auxin and light signaling during adventitious root development. AGO1 seems to be targeted for degradation by silencing suppressor F-box-containing proteins from Turnip yellow virus and Cucurbit aphid-borne yellow virus.
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Identifiers

Identifier Name
aliasAtAGO1
aliasAGO1
aliasICU9
aliasARGONAUTE 1
uniprotO04379

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0016441IEPGene Ontologyposttranscriptional gene silencing1
GO:0035195IMP, IEP, IGIUniProtgene silencing by miRNA1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0009733IGIUniProtresponse to auxin1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0009850IGIUniProtauxin metabolic process1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0010218IGI, RCA, UniProtresponse to far red light1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
GO:0048830IMPUniProtadventitious root development1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0009616IDA, RCA, UniProtvirus induced gene silencing1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
GO:0016246IMP, RCA, UniProtRNA interference1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
GO:0048864IGIUniProtstem cell development1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0045087IMPGene Ontologyinnate immune response1
GO:0006306RCAGene OntologyDNA methylation1
GO:0006342RCAGene Ontologychromatin silencing1
GO:0006346RCAGene Ontologymethylation-dependent chromatin silencing1
GO:0007062RCAGene Ontologysister chromatid cohesion1
GO:0007155RCAGene Ontologycell adhesion1
GO:0007267RCAGene Ontologycell-cell signaling1
GO:0009793IGI, RCA, UniProtembryo development ending in seed dormancy1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
GO:0009855RCAGene Ontologydetermination of bilateral symmetry1
GO:0009880RCAGene Ontologyembryonic pattern specification1
GO:0009887RCAGene Ontologyorgan morphogenesis1
GO:0009926RCAGene Ontologyauxin polar transport1
GO:0009965IMP, RCA, UniProtleaf morphogenesis1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
GO:0010014RCAGene Ontologymeristem initiation1
GO:0010050RCAGene Ontologyvegetative phase change1
GO:0010051RCAGene Ontologyxylem and phloem pattern formation1
GO:0010072RCAGene Ontologyprimary shoot apical meristem specification1
GO:0010073RCAGene Ontologymeristem maintenance1
GO:0010090RCAGene Ontologytrichome morphogenesis1
GO:0010228RCAGene Ontologyvegetative to reproductive phase transition of meristem1
GO:0010267RCAGene Ontologyproduction of ta-siRNAs involved in RNA interference1
GO:0010431RCAGene Ontologyseed maturation1
GO:0016569RCAGene Ontologycovalent chromatin modification1
GO:0031047IEA, RCAUniProtgene silencing by RNA1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0035196RCAGene Ontologyproduction of miRNAs involved in gene silencing by miRNA1
GO:0045010RCAGene Ontologyactin nucleation1
GO:0045595RCAGene Ontologyregulation of cell differentiation1
GO:0048439RCAGene Ontologyflower morphogenesis1
GO:0048519RCAGene Ontologynegative regulation of biological process1
GO:0048765RCAGene Ontologyroot hair cell differentiation1
GO:0051301RCAGene Ontologycell division1
GO:0071555RCAGene Ontologycell wall organization1
GO:0009955IMPUniProtadaxial/abaxial pattern specification1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0010305IMPUniProtleaf vascular tissue pattern formation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0010589IMPUniProtleaf proximal/distal pattern formation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0006952IEAUniProtdefense response1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0019048IEAUniProtmodulation by virus of host morphology or physiology1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0007275IEAUniProtmulticellular organismal development1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0006355IEAUniProtregulation of transcription, DNA-dependent1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0006417IEAUniProtregulation of translation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0006351IEAUniProttranscription, DNA-templated1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004521IDAUniProtendoribonuclease activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0035197IPIUniProtsiRNA binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0035198IPIUniProtmiRNA binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0005515IPI, IEAGene Ontologyprotein binding1
GO:0003723IEAUniProtRNA binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0003676IEAInterPronucleic acid binding

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737IEA, IDA, ISM, TASUniProtcytoplasm1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0005634IDAUniProtnucleus1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0005829IDAUniProtcytosol1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0019898IDAUniProtextrinsic to membrane1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0030529IEAUniProtribonucleoprotein complex1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR024357Argonaut, glycine-rich domain
IPR014811Domain of unknown function DUF1785
IPR012337Ribonuclease H-like domain
IPR003165Stem cell self-renewal protein Piwi
IPR003100Argonaute/Dicer protein, PAZ domain

Mapman id Description
33.99development.unspecified
No SignalP domains detected for this gene.