Gene: AT1G26830 (Arabidopsis thaliana)

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Gene Identifier
AT1G26830
Transcript Identifier
AT1G26830.1
Gene Type
Coding gene
Location
1 : 9296063-9298374 : positive

Family

Gene family
HOM03M000391
(156 genes in 16 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
cullin 3
Curated Summary
Cullin, putative, similar to Cullin homolog 3 (CUL-3) SP:Q13618, GI:3639052 from (Homo sapiens); contains Pfam profile PF00888: Cullin family. Interacts with other components of E3 ligase complex suggesting it functions in RUB-modification. Forms complexes with BTB domain proteins forming a novel class of E3-based ubiquitin protein-ligase complexes. Mutant is early flowering and has a reduced sensitivity to far-red light. cul3a/cul3b homozygous/heterozygous plants are embryo lethal.
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Identifiers

Identifier Name
aliasCUL3
aliascullin 3
aliascullin 3A
aliasCUL3A
aliasATCUL3A
aliasATCUL3
uniprotQ9ZVH4

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006511IEA, TASUniProtubiquitin-dependent protein catabolic process1 2 3 4 5 6 7 8 9
GO:0009639IMP, RCA, UniProtresponse to red or far red light1 2 3 4 5 6 7 8 9 10
GO:0009911IMPUniProtpositive regulation of flower development1 2 3 4 5 6 7 8 9
GO:0009793IGIUniProtembryo development ending in seed dormancy1 2 3 4 5 6 7 8 9
GO:0009960IGIUniProtendosperm development1 2 3 4 5 6 7 8 9
GO:0008284RCAGene Ontologypositive regulation of cell proliferation1
GO:0009630RCAGene Ontologygravitropism1
GO:0044265IEAPLAZA Homologycellular macromolecule catabolic processHOM03M000391
GO:0030163IEAPLAZA Homologyprotein catabolic processHOM03M000391
GO:0051603IEAPLAZA Homologyproteolysis involved in cellular protein catabolic processHOM03M000391
GO:0019941IEAPLAZA Homologymodification-dependent protein catabolic processHOM03M000391
GO:0044257IEAPLAZA Homologycellular protein catabolic processHOM03M000391
GO:0043632IEAPLAZA Homologymodification-dependent macromolecule catabolic processHOM03M000391

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004842ISSGene Ontologyubiquitin-protein ligase activity1
GO:0005515IPIGene Ontologyprotein binding1
GO:0031625IEAInterProubiquitin protein ligase binding
GO:0044389IEAPLAZA Homologysmall conjugating protein ligase bindingHOM03M000391
GO:0019899IEAPLAZA Homologyenzyme bindingHOM03M000391

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus1
GO:0000151TASGene Ontologyubiquitin ligase complex1
GO:0019005IPIGene OntologySCF ubiquitin ligase complex1
GO:0005829IDAUniProtcytosol1 2 3 4 5 6 7 8 9
GO:0031461IEAUniProtcullin-RING ubiquitin ligase complex1 2 3 4 5 6 7 8

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001373Cullin, N-terminal
IPR016158Cullin homology
IPR019559Cullin protein, neddylation domain
IPR016159Cullin repeat-like-containing domain
IPR011991Winged helix-turn-helix DNA-binding domain

Mapman id Description
29.5.11.4.5.1protein.degradation.ubiquitin.E3.BTB/POZ Cullin3.Cullin3
No SignalP domains detected for this gene.