Gene: AT1G24470 (Arabidopsis thaliana)

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Gene Identifier
AT1G24470
Transcript Identifier
AT1G24470.1
Gene Type
Coding gene
Location
1 : 8674056-8676277 : positive

Family

Gene family
HOM03M000785
(89 genes in 16 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
beta-ketoacyl reductase 2
Curated Summary
Encodes one of the two Arabidopsis homologues to YBR159w encoding a S. cerevisiae beta-ketoacyl reductase (KCR), which catalyzes the first reduction during VLCFA (very long chain fatty acids, >18 carbon) elongation: KCR1 (At1g67730), KCR2 (At1g24470). Complementation of the yeast ybr159Delta mutant demonstrated that the two KCR proteins are divergent and that only AtKCR1 can restore heterologous elongase activity similar to the native yeast KCR gene.
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Identifiers

Identifier Name
aliasbeta-ketoacyl reductase 2
aliasKCR2
aliasATKCR2
uniprotQ9FYL6

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0016126RCAGene Ontologysterol biosynthetic process1
GO:0046520RCAGene Ontologysphingoid biosynthetic process1
GO:0008152IEAInterPrometabolic process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016491ISS, IEAGene Ontologyoxidoreductase activity1
GO:0045703IDAUniProtketoreductase activity1 2 3 4 5
GO:0018454IMPGene Ontologyacetoacetyl-CoA reductase activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005739ISMGene Ontologymitochondrion1
GO:0005783IDAUniProtendoplasmic reticulum1 2 3 4 5
GO:0005789IEAUniProtendoplasmic reticulum membrane1 2 3 4
GO:0016021IEAUniProtintegral to membrane1 2 3 4

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR016040NAD(P)-binding domain
IPR002347Glucose/ribitol dehydrogenase
IPR002198Short-chain dehydrogenase/reductase SDR
IPR020904Short-chain dehydrogenase/reductase, conserved site

Mapman id Description
26.22misc.short chain dehydrogenase/reductase (SDR)
No SignalP domains detected for this gene.