Gene: AT1G21410 (Arabidopsis thaliana)

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Gene Identifier
AT1G21410
Transcript Identifier
AT1G21410.1
Gene Type
Coding gene
Location
1 : 7497479-7499386 : positive

Family

Gene family
HOM03M002886
(30 genes in 15 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
F-box/RNI-like superfamily protein
Curated Summary
AtSKP2;1 is a homolog of human SKP2, the human F-box protein that recruits E2F1. Contains an F-box motif at the N-terminal region and a C-terminal Leu-rich repeat domain. Forms part of an E3-ubiquitin-ligase SCF (Skp1, cullin, F-box) complex and recruits phosphorylated AtE2Fc, a transcriptional factor that might play a role in cell division and during the transition from skotomorphogenesis to photomorphogenesis. AtSKP2;1 (At1g21410) and AtSKP2;2 (At1g77000) may be duplicated genes.
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Identifiers

Identifier Name
aliasSKP2A
uniprotQ9LPL4

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0031146IDA, IPI, UniProtSCF-dependent proteasomal ubiquitin-dependent protein catabolic process1 2 3 4 5 6 7 8 9
GO:0010311IMPUniProtlateral root formation1 2 3 4 5 6 7 8
GO:0051781IMPUniProtpositive regulation of cell division1 2 3 4 5 6 7 8
GO:0016567IDAGene Ontologyprotein ubiquitination1
GO:0071365IDAUniProtcellular response to auxin stimulus1 2 3 4 5 6 7 8
GO:0045892RCAGene Ontologynegative regulation of transcription, DNA-dependent1
GO:0009734IEAUniProtauxin mediated signaling pathway1 2 3 4 5 6 7
GO:0010286ISOPLAZA Integrative Orthologyheat acclimationAT1G77000
GO:1901332ISOPLAZA Integrative Orthologynegative regulation of lateral root developmentAT1G77000

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005515IPI, IEAGene Ontologyprotein binding1
GO:0004842IDAUniProtubiquitin-protein ligase activity1 2 3 4 5 6 7 8

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1
GO:0019005IDA, IPI, UniProtSCF ubiquitin ligase complex1 2 3 4 5 6 7 8 9
GO:0005634IDAUniProtnucleus1 2 3 4 5 6 7 8

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006553Leucine-rich repeat, cysteine-containing subtype
IPR001810F-box domain

Mapman id Description
29.5.11.4.3.2protein.degradation.ubiquitin.E3.SCF.FBOX
No SignalP domains detected for this gene.