Gene: AT1G17220 (Arabidopsis thaliana)

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Gene Identifier
AT1G17220
Transcript Identifier
AT1G17220.1
Gene Type
Coding gene
Location
1 : 5885383-5890165 : positive

Family

Gene family
HOM03M001906
(42 genes in 16 species)
specific family

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Descriptions

Description
Translation initiation factor 2, small GTP-binding protein
Curated Summary
Encodes a chloroplast localized protein with similarity to translation initiation factor 2. Can complement loss of INFB in E.coli suggesting FUG1 does function as a translation initiation factor in vivo. Identified as a suppressor of the leaf variegation mutant var2-6. Suppression is only seen in hypomorphs as complete loss of function alleles are embryo lethal.
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Identifiers

Identifier Name
aliasFUG1
aliasfu-gaeri1
uniprotQ9SHI1

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006413IGI, IEAGene Ontologytranslational initiation1
GO:0009902RCAGene Ontologychloroplast relocation1
GO:0010027RCAGene Ontologythylakoid membrane organization1
GO:0010155RCAGene Ontologyregulation of proton transport1
GO:0019288RCAGene Ontologyisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway1
GO:0034660RCAGene OntologyncRNA metabolic process1
GO:0042793RCAGene Ontologytranscription from plastid promoter1
GO:0046777RCAGene Ontologyprotein autophosphorylation1
GO:0006184IEAUniProtGTP catabolic process1 2 3

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003743IGI, ISSIEA, UniProttranslation initiation factor activity1 2 3 4 5
GO:0005525IEAUniProtGTP binding1 2 3
GO:0003924IEAUniProtGTPase activity1 2 3

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009507IDA, ISMGene Ontologychloroplast1 2
GO:0009941IDAUniProtchloroplast envelope1 2 3 4
GO:0009570IDAUniProtchloroplast stroma1 2 3 4
GO:0005622IEAInterProintracellular

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR015760Translation initiation factor IF- 2
IPR006847Translation initiation factor IF-2, N-terminal
IPR000178Translation initiation factor aIF-2, bacterial-like
IPR004161Translation elongation factor EFTu/EF1A, domain 2
IPR000795Elongation factor, GTP-binding domain
IPR023115Translation initiation factor IF- 2, domain 3
IPR009000Translation protein, beta-barrel domain
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR005225Small GTP-binding protein domain

Mapman id Description
29.2.3protein.synthesis.initiation
SignalP Description
SignalP-noTMSignal Peptide detected using noTM network