Gene: AT1G16420 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G16420
Transcript Identifier
AT1G16420.1
Gene Type
Coding gene
Location
1 : 5612304-5613829 : negative

Family

Gene family
HOM03M001266
(59 genes in 15 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
metacaspase 8
Curated Summary
Encodes a metacaspase (cysteine-type endopeptidase) that is involved in promoting programmed cell death in response to hydrogen peroxide (H2O2), UV light, and methyl viologen (MV). Transcript levels rise in response to UV-C, H2O2, and MV. In vitro assays demonstrate that this enzyme has a preference for cleaving after an arginine residue, and it has a pH optimum of 8.0.
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Identifiers

Identifier Name
aliasATMC8
aliasMC8
aliasARABIDOPSIS THALIANA METACASPASE 8
aliasmetacaspase 2e
aliasMCP2e
aliasAtMCP2e
aliasmetacaspase 8
uniprotQ9SA41

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006979IEP, IMPGene Ontologyresponse to oxidative stress1 2
GO:0010225IEPUniProtresponse to UV-C1 2 3 4 5
GO:0010421IMPUniProthydrogen peroxide-mediated programmed cell death1 2 3 4 5
GO:0012501IMPGene Ontologyprogrammed cell death1
GO:0042542IMPGene Ontologyresponse to hydrogen peroxide1
GO:0006508IEAUniProtproteolysis1 2 3 4

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004197IDA, IEA, UniProtcysteine-type endopeptidase activity1 2 3 4 5

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005576ISMGene Ontologyextracellular region1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011600Peptidase C14, caspase domain

Mapman id Description
29.5protein.degradation
No SignalP domains detected for this gene.