Gene: AT1G15750 (Arabidopsis thaliana)

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Gene Identifier
AT1G15750
Transcript Identifier
AT1G15750.1
Gene Type
Coding gene
Location
1 : 5415086-5420359 : negative

Family

Gene family
HOM03M000684
(100 genes in 14 species)
specific family
Subfamily
ORTHO03M000326
(16 genes in 8 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
Transducin family protein / WD-40 repeat family protein
Curated Summary
Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top half of the embryo during the transition stage of embryogenesis. It can also interact with IAA12 through the EAR domain of IAA12 and the CTLH domain of TPL. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.
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Identifiers

Identifier Name
aliasTPL
aliasTOPLESS
aliasWSIP1
aliasWUS-INTERACTING PROTEIN 1
uniprotQ94AI7

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0010072IMP, IGIUniProtprimary shoot apical meristem specification1 2 3 4 5 6 7 8 9 10 11 12
GO:0009733IPIUniProtresponse to auxin1 2 3 4 5 6 7 8 9 10 11
GO:0010051IGIUniProtxylem and phloem pattern formation1 2 3 4 5 6 7 8 9 10 11
GO:0045892IDAUniProtnegative regulation of transcription, DNA-dependent1 2 3 4 5 6 7 8 9 10 11
GO:0009867IMPUniProtjasmonic acid mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11
GO:0006351IEAUniProttranscription, DNA-templated1 2 3 4 5 6 7 8 9 10
GO:0006355IEAInterProregulation of transcription, DNA-dependent
GO:2001141IEAPLAZA Homologyregulation of RNA biosynthetic processHOM03M000684

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005515IPI, IEAGene Ontologyprotein binding1
GO:0042803IPIGene Ontologyprotein homodimerization activity1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISM, UniProtnucleus1 2 3 4 5 6 7 8 9 10 11 12
GO:0005829IDAUniProtcytosol1 2 3 4 5 6 7 8 9 10 11

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR027728Topless family
IPR001680WD40 repeat
IPR006594LisH dimerisation motif
IPR017986WD40-repeat-containing domain
IPR015943WD40/YVTN repeat-like-containing domain
IPR019775WD40 repeat, conserved site
IPR006595CTLH, C-terminal LisH motif

Mapman id Description
33.99development.unspecified
No SignalP domains detected for this gene.