Gene: AT1G13950 (Arabidopsis thaliana)

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Gene Identifier
AT1G13950
Transcript Identifier
AT1G13950.1
Gene Type
Coding gene
Location
1 : 4773631-4774668 : positive

Family

Gene family
HOM03M000940
(74 genes in 16 species)
specific family
Subfamily
ORTHO03M001015
(11 genes in 8 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
eukaryotic elongation factor 5A-1
Curated Summary
Encodes eukaryotic translation initiation factor 5A (EIF-5A).In mammalian cells it functions as a shuttle protein that translocates mRNA from the nucleus to cytoplasmic ribosomes. Overexpression results in an increase in both primary and secondary xylem formation. In RNAi suppressed lines, xylem formation is reduced.
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Identifiers

Identifier Name
aliasELF5A-1
aliasEUKARYOTIC ELONGATION FACTOR 5A-1
aliasEUKARYOTIC ELONGATION FACTOR 5A
aliasEIF5A
aliasATELF5A-1
aliaseukaryotic elongation factor 5A-1
aliasEIF-5A
uniprotQ9XI91

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006413ISSGene Ontologytranslational initiation1
GO:0010089IMPUniProtxylem development1 2 3 4
GO:0008612IEAUniProtpeptidyl-lysine modification to hypusine1 2 3
GO:0045901IEAUniProtpositive regulation of translational elongation1 2 3
GO:0045905IEAUniProtpositive regulation of translational termination1 2 3
GO:0006452IEAUniProttranslational frameshifting1 2 3
GO:0006449IEAPLAZA Homologyregulation of translational terminationHOM03M000940
GO:0046516IEAPLAZA Homologyhypusine metabolic processHOM03M000940

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003743IEA, ISSUniProttranslation initiation factor activity1 2 3 4
GO:0043022IEAUniProtribosome binding1 2 3
GO:0003746IEAUniProttranslation elongation factor activity1 2 3
GO:0003723IEAInterProRNA binding

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001884Translation elongation factor IF5A
IPR020189Translation elongation factor, IF5A C-terminal
IPR019769Translation elongation factor, IF5A, hypusine site
IPR008991Translation protein SH3-like domain
IPR012340Nucleic acid-binding, OB-fold
IPR014722Ribosomal protein L2 domain 2

Mapman id Description
29.2.3protein.synthesis.initiation
No SignalP domains detected for this gene.