Gene: AT1G08260 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G08260
Transcript Identifier
AT1G08260.1
Gene Type
Coding gene
Location
1 : 2590944-2606892 : positive

Family

Gene family
HOM03M003666
(25 genes in 16 species)
specific family

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Descriptions

Description
DNA polymerase epsilon catalytic subunit
Curated Summary
Similar to POL2A, DNA polymerase epsilon catalytic subunit. Essential for Arabidopsis growth. Null homozygotes are embryo lethal, partial loss of function alleles show embryo patterning defects such as root pole displacement. Delayed progression through cell cycle results in embryos with smaller numbers of larger cells.
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Identifiers

Identifier Name
aliasESD7
aliasTILTED 1
aliasPOL2A
aliasEMB2284
aliasTIL1
aliasEMBRYO DEFECTIVE 529
aliasEMB529
aliasABA OVERLY SENSITIVE 4
aliasEMBRYO DEFECTIVE 2284
aliasEARLY IN SHORT DAYS 7
aliasEMB142
aliasEMBRYO DEFECTIVE 142
aliasABO4
uniprotF4HW04

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009793IMP, NASGene Ontologyembryo development ending in seed dormancy1 2
GO:0010086IMPGene Ontologyembryonic root morphogenesis1
GO:0051302IMPGene Ontologyregulation of cell division1
GO:0048579IMPGene Ontologynegative regulation of long-day photoperiodism, flowering1
GO:0006260IEA, RCAUniProtDNA replication1 2 3 4 5 6
GO:0006306RCAGene OntologyDNA methylation1
GO:0008283RCAGene Ontologycell proliferation1
GO:0051567RCAGene Ontologyhistone H3-K9 methylation1
GO:0006139IEAInterPronucleobase-containing compound metabolic process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003887IEA, ISSUniProtDNA-directed DNA polymerase activity1 2 3 4 5 6
GO:0051539IEAUniProt4 iron, 4 sulfur cluster binding1 2 3 4 5
GO:0003677IEAUniProtDNA binding1 2 3 4 5
GO:0000166IEAUniProtnucleotide binding1 2 3 4 5
GO:0008270IEAUniProtzinc ion binding1 2 3 4 5
GO:0003676IEAInterPronucleic acid binding
GO:1901265IEAPLAZA Homologynucleoside phosphate bindingHOM03M003666

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISM, IEAGene Ontologynucleus1
GO:0008622IDA, IPIUniProtepsilon DNA polymerase complex1 2 3 4 5 6
GO:0048046IDAGene Ontologyapoplast1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR012337Ribonuclease H-like domain
IPR006172DNA-directed DNA polymerase, family B
IPR006133DNA-directed DNA polymerase, family B, exonuclease domain
IPR006134DNA-directed DNA polymerase, family B, multifunctional domain
IPR013697DNA polymerase epsilon, catalytic subunit A, C-terminal

Mapman id Description
28.1DNA.synthesis/chromatin structure
No SignalP domains detected for this gene.