Gene: AT1G08030 (Arabidopsis thaliana)

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Gene Identifier
AT1G08030
Transcript Identifier
AT1G08030.1
Gene Type
Coding gene
Location
1 : 2489575-2492741 : negative

Family

Gene family
HOM03M004741
(20 genes in 16 species)
specific family

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Descriptions

Description
tyrosylprotein sulfotransferase
Curated Summary
Encodes a tyrosylprotein sulfotransferase (TPST). This protein is a 500-aa type I transmembrane protein that shows no sequence similarity to animal TPSTs. Activity confirmed by protein expression in yeast. TPST is expressed throughout the plant body, and the highest levels of expression are in the root apical meristem. TPST acts in the auxin pathway to maintain postembryonic root stem cell niche by defining the expression of the PLETHORA stem cell transcription factor genes. A loss-of-function mutant TPST displayed a marked dwarf phenotype accompanied by stunted roots, pale green leaves, reduction in higher order veins, early senescence, and a reduced number of flowers and siliques.
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Identifiers

Identifier Name
aliasTPST
aliasAQC1
aliastyrosylprotein sulfotransferase
aliasactive quiescent center1
uniprotQ3EDG5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009733IEPGene Ontologyresponse to auxin1
GO:0010082IMPGene Ontologyregulation of root meristem growth1
GO:0010468IMPGene Ontologyregulation of gene expression1
GO:0019827IMPGene Ontologystem cell maintenance1
GO:0045087IMPGene Ontologyinnate immune response1
GO:0006007RCAGene Ontologyglucose catabolic process1
GO:0006486RCAGene Ontologyprotein glycosylation1
GO:0007346RCAGene Ontologyregulation of mitotic cell cycle1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008476IEA, IDAUniProtprotein-tyrosine sulfotransferase activity1 2 3 4
GO:0008146IEAInterProsulfotransferase activity

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005794IDAGene OntologyGolgi apparatus1
GO:0005768IDAGene Ontologyendosome1
GO:0005802IDAGene Ontologytrans-Golgi network1
GO:0000139IEAUniProtGolgi membrane1 2 3
GO:0016021IEAUniProtintegral to membrane1 2 3

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR005331Sulfotransferase
IPR010635Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase

Mapman id Description
35.2not assigned.unknown
SignalP Description
SignalP-noTMSignal Peptide detected using noTM network