PLAZA 3.0 Monocots gene overview : AT1G04450

Gene: AT1G04450 (Arabidopsis thaliana)

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Curated Summary: Encodes a member of a novel protein family that contains contain a CRIB (for Cdc42/Rac-interactive binding) motif required for their specific interaction with GTP-bound Rop1 (plant-specific Rho GTPase). It interacts with Rop1 and is involved in pollen tube growth and function, and exocytosis in the pollen tube tip. The protein most similar to RIC1 (family subgroup III). Gene is expressed predominantly in inflorescence and flower tissue. Interacts with ROP1 to modulate calcium ion influxes required to generate tip-focused calcium gradients.It

Identifier	Name
alias	RIC3
alias	ROP-interactive CRIB motif-containing protein 3
uniprot	F4I5N6

GO term	Evidence(s)	Provider	Description	Source
GO:0009860	IMP	UniProt	pollen tube growth	1 2 3 4 5
GO:0007204	IMP	UniProt	positive regulation of cytosolic calcium ion concentration	1 2 3 4 5
GO:0030834	IMP	UniProt	regulation of actin filament depolymerization	1 2 3 4 5
GO:0050848	IMP	Gene Ontology	regulation of calcium-mediated signaling	1
GO:0050850	IMP	UniProt	positive regulation of calcium-mediated signaling	1 2 3 4 5
GO:0017157	IDA	UniProt	regulation of exocytosis	1 2 3 4 5
GO:0051650	IDA	UniProt	establishment of vesicle localization	1 2 3 4 5
GO:0040008	IEA	UniProt	regulation of growth	1 2 3 4

GO term	Evidence(s)	Provider	Description	Source
GO:0005515	IPI	Gene Ontology	protein binding	1

GO term	Evidence(s)	Provider	Description	Source
GO:0005634	ISM	Gene Ontology	nucleus	1
GO:0005737	IDA	UniProt	cytoplasm	1 2 3 4 5

Experimental Evidence

Electronic Evidence

Computational Reviewed Evidence

InterPro	Description
IPR000095	CRIB domain

Mapman id	Description
30.5	signalling.G-proteins

No SignalP domains detected for this gene.