Gene: AT1G03090 (Arabidopsis thaliana)

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Gene Identifier
Transcript Identifier
Gene Type
Coding gene
1 : 739715-743819 : positive


Gene family
(74 genes in 16 species)
specific family

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methylcrotonyl-CoA carboxylase alpha chain, mitochondrial / 3-methylcrotonyl-CoA carboxylase 1 (MCCA)
Curated Summary
MCCA is the biotinylated subunit of the dimer MCCase, which is involved in leucine degradation. Both subunits are nuclear coded and the active enzyme is located in the mitochondrion.
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Identifier Name





Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006552IDAUniProtleucine catabolic process1 2 3 4 5 6
GO:0009744RCAGene Ontologyresponse to sucrose1
GO:0009750RCAGene Ontologyresponse to fructose1
GO:0008152IEAInterPrometabolic process
GO:1901576IEAPLAZA Homologyorganic substance biosynthetic processHOM03M000960
GO:0044711IEAPLAZA Homologysingle-organism biosynthetic processHOM03M000960
GO:0044238IEAPLAZA Homologyprimary metabolic processHOM03M000960
GO:0019752IEAPLAZA Homologycarboxylic acid metabolic processHOM03M000960

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004485IDAUniProtmethylcrotonoyl-CoA carboxylase activity1 2 3 4 5 6
GO:0050897IDAUniProtcobalt ion binding1 2 3 4 5 6
GO:0005524IEAUniProtATP binding1 2 3 4 5
GO:0004075IEAUniProtbiotin carboxylase activity1 2 3 4 5
GO:0016874IEAInterProligase activity
GO:0003824IEAInterProcatalytic activity
GO:0046872IEAInterPrometal ion binding
GO:0016885IEAPLAZA Homologyligase activity, forming carbon-carbon bondsHOM03M000960

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005739IDA, ISM, UniProtmitochondrion1 2 3 4 5 6 7
GO:0022626IDAUniProtcytosolic ribosome1 2 3 4 5 6
GO:0005759IEAUniProtmitochondrial matrix1 2 3 4 5

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR005479Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
IPR013815ATP-grasp fold, subdomain 1
IPR011053Single hybrid motif
IPR016185Pre-ATP-grasp domain
IPR005482Biotin carboxylase, C-terminal
IPR000089Biotin/lipoyl attachment
IPR011761ATP-grasp fold
IPR011764Biotin carboxylation domain
IPR013816ATP-grasp fold, subdomain 2
IPR001882Biotin-binding site
IPR005481Carbamoyl-phosphate synthase, large subunit, N-terminal
IPR011054Rudiment single hybrid motif

Mapman id Description acid metabolism.degradation.branched chain group.leucine
No SignalP domains detected for this gene.