Gene: AT1G02580 (Arabidopsis thaliana)

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Gene Identifier
AT1G02580
Transcript Identifier
AT1G02580.1
Gene Type
Coding gene
Location
1 : 544796-548994 : positive

Family

Gene family
HOM03M001993
(41 genes in 16 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
SET domain-containing protein
Curated Summary
Encodes a putative transcription factor MEDEA (MEA) that negatively regulates seed development in the absence of fertilization. Mutations in this locus result in embryo lethality. MEA is a Polycomb group gene that is imprinted in the endosperm. The maternal allele is expressed and the paternal allele is silent. MEA is controlled by DEMETER (DME), a DNA glycosylase required to activate MEA expression, and METHYLTRANSFERASE I (MET1), which maintains CG methylation at the MEA locus. MEA is involved in the negative regulation of its own imprinted gene expression; the effect is not only allele-specific but also dynamically regulated during seed development. In the ovule, the MEA transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization
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Identifiers

Identifier Name
aliasEMBRYO DEFECTIVE 173
aliasSET DOMAIN-CONTAINING PROTEIN 5
aliasEMB173
aliasFIS1
aliasSDG5
aliasMEA
aliasFERTILIZATION INDEPENDENT SEED 1
aliasMEDEA
uniprotO65312

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:2000014IMPUniProtregulation of endosperm development1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0009646IEPUniProtresponse to absence of light1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0045892IMPUniProtnegative regulation of transcription, DNA-dependent1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0006349IMP, RCA, UniProtregulation of gene expression by genetic imprinting1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0048317IGIUniProtseed morphogenesis1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0010048RCAGene Ontologyvernalization response1
GO:0016571RCAGene Ontologyhistone methylation1
GO:0034968IEAUniProthistone lysine methylation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0006351IEAUniProttranscription, DNA-templated1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005515IPI, IEAGene Ontologyprotein binding1
GO:0003700ISSUniProtsequence-specific DNA binding transcription factor activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0043565IDAUniProtsequence-specific DNA binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0003682IEAUniProtchromatin binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0018024IEAUniProthistone-lysine N-methyltransferase activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISM, UniProtnucleus1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0031519IEAUniProtPcG protein complex1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR026489CXC domain
IPR001214SET domain
IPR025778Histone-lysine N-methyltransferase, EZ

Mapman id Description
33.99development.unspecified
No SignalP domains detected for this gene.
DatabaseType
PlnTFDBSET