Gene: AT1G01040 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G01040
Transcript Identifier
AT1G01040.2
Gene Type
Coding gene
Location
1 : 23519-31079 : positive

Family

Gene family
HOM03M000334
(174 genes in 15 species)
specific family
Subfamily
ORTHO03M010712
(4 genes in 4 species)
specific family

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Descriptions

Description
dicer-like 1
Curated Summary
Encodes a Dicer homolog. Dicer is a RNA helicase involved in microRNA processing. Mutations in this locus can result in embryo lethality. Embryo shape at seed maturity is globular-elongate. Other mutants convert the floral meristems to an indeterminate state, others yet show defects in ovule development. mRNA is expressed in all shoot tissues. DCL1 is able to produce miRNAs and siRNAs.
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Identifiers

Identifier Name
aliasCAF
aliasEMB60
aliasCARPEL FACTORY
aliasEMBRYO DEFECTIVE 60
aliasSHORT INTEGUMENTS 1
aliasSUSPENSOR 1
aliasEMB76
aliasdicer-like 1
aliasABNORMAL SUSPENSOR 1
aliasATDCL1
aliasDCL1
aliasASU1
aliasSIN1
aliasEMBRYO DEFECTIVE 76
aliasSUS1
aliasDICER-LIKE 1
uniprotQ9SP32

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0010098IMPGene Ontologysuspensor development1
GO:0000910IMPGene Ontologycytokinesis1
GO:0006396IEA, ISS, RCAUniProtRNA processing1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0035279IMPGene OntologymRNA cleavage involved in gene silencing by miRNA1
GO:0031053TASGene Ontologyprimary miRNA processing1
GO:0010267IMP, RCAGene Ontologyproduction of ta-siRNAs involved in RNA interference1 2
GO:0035196IGI, RCAGene Ontologyproduction of miRNAs involved in gene silencing by miRNA1 2
GO:0009616IMP, RCAGene Ontologyvirus induced gene silencing1 2
GO:0030422IMPGene Ontologyproduction of siRNA involved in RNA interference1
GO:0010599IMPGene Ontologyproduction of lsiRNA involved in RNA interference1
GO:2000034IMPGene Ontologyregulation of seed maturation1
GO:0000226RCAGene Ontologymicrotubule cytoskeleton organization1
GO:0000278RCAGene Ontologymitotic cell cycle1
GO:0000911RCAGene Ontologycytokinesis by cell plate formation1
GO:0006306RCAGene OntologyDNA methylation1
GO:0006342RCAGene Ontologychromatin silencing1
GO:0007267RCAGene Ontologycell-cell signaling1
GO:0009630RCAGene Ontologygravitropism1
GO:0010050RCAGene Ontologyvegetative phase change1
GO:0016569RCAGene Ontologycovalent chromatin modification1
GO:0031047IEA, RCAUniProtgene silencing by RNA1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0051607RCAGene Ontologydefense response to virus1
GO:0009880IMPGene Ontologyembryonic pattern specification1
GO:0009908TASGene Ontologyflower development1
GO:0010228IMPGene Ontologyvegetative to reproductive phase transition of meristem1
GO:0090305IEAUniProtnucleic acid phosphodiester bond hydrolysis1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0016075IEAUniProtrRNA catabolic process1 2 3 4 5 6 7 8 9 10 11 12 13

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004525IEA, ISSUniProtribonuclease III activity1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0008026ISSGene OntologyATP-dependent helicase activity1
GO:0003725IDAGene Ontologydouble-stranded RNA binding1
GO:0005515IPI, IEAGene Ontologyprotein binding1
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0003677IEAUniProtDNA binding1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0004386IEAUniProthelicase activity1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0003723IEAUniProtRNA binding1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0016787IEAInterProhydrolase activity
GO:0016891IEAInterProendoribonuclease activity, producing 5'-phosphomonoesters
GO:0003676IEAInterPronucleic acid binding
GO:0016893IEAPLAZA Homologyendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersHOM03M000334
GO:0004521IEAPLAZA Homologyendoribonuclease activityHOM03M000334

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IEA, IDA, ISMUniProtnucleus1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0010445IDAGene Ontologynuclear dicing body1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000999Ribonuclease III domain
IPR001650Helicase, C-terminal
IPR014001Helicase, superfamily 1/2, ATP-binding domain
IPR011907Ribonuclease III
IPR005034Dicer dimerisation domain
IPR006935Helicase/UvrB domain
IPR003100Argonaute/Dicer protein, PAZ domain
IPR014720Double-stranded RNA-binding domain
IPR027417P-loop containing nucleoside triphosphate hydrolase

Mapman id Description
27.1.20RNA.processing.degradation dicer
No SignalP domains detected for this gene.