Gene: AT5G57160 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G57160
Transcript Identifier
AT5G57160.1
Gene Type
Coding gene
Location
5 : 23155150-23161688 : negative

Family

Gene family
HOM03D004481
(44 genes in 30 species)
specific family
Subfamily
ORTHO03D004280
(36 genes in 30 species)
specific family

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Descriptions

Description
DNA ligase IV
Curated Summary
Encodes the Arabidopsis orthologue of the yeast and mammalian DNA ligase IV. Involved in the repair of DNA damage but, unlike in yeast, not required for T-DNA integration. Interacts with the Arabidopsis homologue of XRCC4.
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Identifiers

Identifier Name
aliasDNA LIGASE IV
aliasLIG4
aliasATLIG4
uniprotQ9LL84

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006266IBAGene OntologyDNA ligation1
GO:0006974IMPGene Ontologycellular response to DNA damage stimulus1
GO:0010165IMPUniProtresponse to X-ray1 2 3 4 5 6
GO:0015074IMPGene OntologyDNA integration1
GO:0000723IMPGene Ontologytelomere maintenance1
GO:0006302IMPUniProtdouble-strand break repair1 2 3 4 5 6
GO:0006260IEAUniProtDNA replication1 2 3 4 5
GO:0006281IEAInterProDNA repair
GO:0051103IEAUniProtDNA ligation involved in DNA repair1 2 3 4 5
GO:0006310IEAUniProtDNA recombination1 2 3 4 5

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003910IDA, IEA, UniProtDNA ligase (ATP) activity1 2 3 4 5 6
GO:0005515IPIGene Ontologyprotein binding1
GO:0003909IEAInterProDNA ligase activity
GO:0005524IEAUniProtATP binding1 2 3 4 5
GO:0003677IEAUniProtDNA binding1 2 3 4 5
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus1
GO:0032807IBAUniProtDNA ligase IV complex1 2 3 4 5 6
GO:0009506IDAUniProtplasmodesma1 2 3 4 5 6
GO:0048046IDAUniProtapoplast1 2 3 4 5 6

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001357BRCT domain
IPR016059DNA ligase, ATP-dependent, conserved site
IPR000977DNA ligase, ATP-dependent
IPR012340Nucleic acid-binding, OB-fold
IPR012308DNA ligase, ATP-dependent, N-terminal
IPR012310DNA ligase, ATP-dependent, central
IPR012309DNA ligase, ATP-dependent, C-terminal

Mapman id Description
28.1DNA.synthesis/chromatin structure
No SignalP domains detected for this gene.