Gene: AT5G48820 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G48820
Transcript Identifier
AT5G48820.2
Gene Type
Coding gene
Location
5 : 19792608-19794346 : negative

Family

Gene family
HOM03D000965
(154 genes in 28 species)
specific family
Subfamily
ORTHO03D011776
(22 genes in 19 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
inhibitor/interactor with cyclin-dependent kinase
Curated Summary
Kip-related protein (KRP) gene, encodes CDK (cyclin-dependent kinase) inhibitor (CKI), negative regulator of cell division. Binds to D type and CDC2A cyclins and may inhibit cell cycle. Seven KRP genes were found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization.
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Identifiers

Identifier Name
aliasKIP-RELATED PROTEIN 3
aliasinhibitor/interactor with cyclin-dependent kinase
aliasICK6
aliasKRP3
uniprotQ9FKB5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0045736IDA, RCA, TASGene Ontologynegative regulation of cyclin-dependent protein serine/threonine kinase activity1 AGRICOLA_IND:IND233052532 3
GO:0000278RCAGene Ontologymitotic cell cycle1
GO:0000280RCAGene Ontologynuclear division1
GO:0000911RCAGene Ontologycytokinesis by cell plate formation1
GO:0006275RCAGene Ontologyregulation of DNA replication1
GO:0006342RCAGene Ontologychromatin silencing1
GO:0010389RCAGene Ontologyregulation of G2/M transition of mitotic cell cycle1
GO:0010440RCAGene Ontologystomatal lineage progression1
GO:0016569RCAGene Ontologycovalent chromatin modification1
GO:0031047RCAGene Ontologygene silencing by RNA1
GO:0042023RCAGene OntologyDNA endoreduplication1
GO:0051225RCAGene Ontologyspindle assembly1
GO:0007050IEAUniProtcell cycle arrest1 2 3 4 5 6
GO:0006469IEAUniProtnegative regulation of protein kinase activity1 2 3 4 5 6
GO:0048519IEAPLAZA Homologynegative regulation of biological processHOM03D000965
GO:0051726IEAPLAZA Homologyregulation of cell cycleHOM03D000965
GO:0048523IEAPLAZA Homologynegative regulation of cellular processHOM03D000965
GO:0022402IEAPLAZA Homologycell cycle processHOM03D000965
GO:0045786IEAPLAZA Homologynegative regulation of cell cycleHOM03D000965
GO:0007049IEAPLAZA Homologycell cycleHOM03D000965

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004861IEA, IGI, TASUniProtcyclin-dependent protein serine/threonine kinase inhibitor activity1 AGRICOLA_IND:IND233052532 3 4 5 6 7 8
GO:0030332IPIGene Ontologycyclin binding1 AGRICOLA_IND:IND23305253
GO:0005515IPIGene Ontologyprotein binding1
GO:0019207IEAPLAZA Homologykinase regulator activityHOM03D000965
GO:0019887IEAPLAZA Homologyprotein kinase regulator activityHOM03D000965
GO:0016538IEAPLAZA Homologycyclin-dependent protein serine/threonine kinase regulator activityHOM03D000965
GO:0004857IEAPLAZA Homologyenzyme inhibitor activityHOM03D000965
GO:0019210IEAPLAZA Homologykinase inhibitor activityHOM03D000965
GO:0030291IEAPLAZA Homologyprotein serine/threonine kinase inhibitor activityHOM03D000965
GO:0004860IEAPLAZA Homologyprotein kinase inhibitor activityHOM03D000965

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISM, IEAGene Ontologynucleus1 2
GO:0005654IEAUniProtnucleoplasm1 2 3 4 5 6

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003175Cyclin-dependent kinase inhibitor

Mapman id Description
31.3cell.cycle
No SignalP domains detected for this gene.