Gene: AT5G48230 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G48230
Transcript Identifier
AT5G48230.2
Gene Type
Coding gene
Location
5 : 19552570-19555122 : negative

Family

Gene family
HOM03D000780
(179 genes in 31 species)
specific family
Subfamily
ORTHO03D000866
(64 genes in 30 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
acetoacetyl-CoA thiolase 2
Curated Summary
Encodes an acetoacetyl-CoA thiolase that generates the bulk of the acetoacetyl-CoA precursor needed for the cytosolic localized, mevalonate-derived isoprenoids biosynthetic pathway. Loss-of-function mutants are embryo lethal.
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Identifiers

Identifier Name
aliasAACT2
aliasEMB1276
aliasEMBRYO DEFECTIVE 1276
aliasACAT2
aliasAcetoacetyl-CoA thiolase 2
aliasacetoacetyl-CoA thiolase 2
uniprotQ8S4Y1

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009793NASGene Ontologyembryo development ending in seed dormancy1
GO:0008152IDA, IGI, IEAGene Ontologymetabolic process1 2
GO:0009846IMPUniProtpollen germination1 2 3
GO:0009860IMPUniProtpollen tube growth1 2 3
GO:0016125IMPUniProtsterol metabolic process1 2 3
GO:0006084RCAGene Ontologyacetyl-CoA metabolic process1
GO:0006085RCAGene Ontologyacetyl-CoA biosynthetic process1
GO:0016126RCAGene Ontologysterol biosynthetic process1
GO:0016132RCAGene Ontologybrassinosteroid biosynthetic process1
GO:0019745RCAGene Ontologypentacyclic triterpenoid biosynthetic process1
GO:0008299IEAUniProtisoprenoid biosynthetic process1 2

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003985IDA, IGIISS, UniProtacetyl-CoA C-acetyltransferase activity1 2 3 4 5
GO:0016747IEAInterProtransferase activity, transferring acyl groups other than amino-acyl groups
GO:0003824IEAInterProcatalytic activity
GO:0046872IEAUniProtmetal ion binding1 2
GO:0016746IEAPLAZA Homologytransferase activity, transferring acyl groupsHOM03D000780

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1
GO:0005886IDAUniProtplasma membrane1 2 3
GO:0005777IDAUniProtperoxisome1 2 3
GO:0005829IDAUniProtcytosol1 2 3

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR020613Thiolase, conserved site
IPR016038Thiolase-like, subgroup
IPR002155Thiolase
IPR016039Thiolase-like
IPR020610Thiolase, active site
IPR020615Thiolase, acyl-enzyme intermediate active site
IPR020616Thiolase, N-terminal
IPR020617Thiolase, C-terminal

Mapman id Description
16.1.2.1secondary metabolism.isoprenoids.mevalonate pathway.acetyl-CoA C-acyltransferase
No SignalP domains detected for this gene.