Gene: AT5G44610 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G44610
Transcript Identifier
AT5G44610.1
Gene Type
Coding gene
Location
5 : 17993718-17994224 : negative

Family

Gene family
HOM03D013035
(4 genes in 4 species)
specific family

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Descriptions

Description
microtubule-associated protein 18
Curated Summary
Encodes a protein with seven repeated VEEKK motifs. RNAi and overexpression experiments suggest that the gene is not involved in cell division but might be consequential for cell shape of epidermal and cortical cells. The protein encoded by this gene binds to cortical microtubules and inhibits tubulin polymerization. Associates to the plasma membrane and interacts with calmodulin and phosphatidylinositol phosphates, indicating an involvement in cellular signal transduction. Expression is enhanced by abiotic and hormonal factors. Induced during senescence.
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Identifiers

Identifier Name
aliasPCAP2
aliasPLASMA MEMBRANE ASSOCIATED CA2+-BINDING PROTEIN-2
aliasMAP18
aliasmicrotubule-associated protein 18

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0000902IMPGene Ontologycell morphogenesis1
GO:0031115IDAGene Ontologynegative regulation of microtubule polymerization1
GO:0043622IMPGene Ontologycortical microtubule organization1
GO:0051301IMPGene Ontologycell division1
GO:0007165TASGene Ontologysignal transduction1
GO:0009409IEPGene Ontologyresponse to cold1
GO:0009651IEPGene Ontologyresponse to salt stress1
GO:0009737IEPGene Ontologyresponse to abscisic acid1
GO:0009739IEPGene Ontologyresponse to gibberellin stimulus1
GO:0010038IEPGene Ontologyresponse to metal ion1
GO:0010150IEPGene Ontologyleaf senescence1
GO:0000041RCAGene Ontologytransition metal ion transport1
GO:0006826RCAGene Ontologyiron ion transport1
GO:0009653RCAGene Ontologyanatomical structure morphogenesis1
GO:0010106RCAGene Ontologycellular response to iron ion starvation1
GO:0010167RCAGene Ontologyresponse to nitrate1
GO:0015706RCAGene Ontologynitrate transport1
GO:0048364RCAGene Ontologyroot development1
GO:0048869RCAGene Ontologycellular developmental process1
GO:0048768IMPGene Ontologyroot hair cell tip growth1
GO:0051716IEAInterProcellular response to stimulus

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008017IDAGene Ontologymicrotubule binding1
GO:0005516IDAGene Ontologycalmodulin binding1
GO:0005545IDAGene Ontology1-phosphatidylinositol binding1
GO:0038023IDAGene Ontologysignaling receptor activity1
GO:1901981IDAGene Ontologyphosphatidylinositol phosphate binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886IDAGene Ontologyplasma membrane1
GO:0090406IDAGene Ontologypollen tube1
GO:0046658IEAInterProanchored to plasma membrane

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR008469DREPP family

Mapman id Description
31.99cell.unspecified
No SignalP domains detected for this gene.