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WorkbenchGene: AT5G41360 (Arabidopsis thaliana)
Overview 
- Gene Identifier
- AT5G41360
- Transcript Identifier
- AT5G41360.1
- Gene Type
- Coding gene
- Location
- 5 : 16544574-16549121 : positive
Family
- Gene family
- Duplication type
- Tandem duplicate
Descriptions
- Description
-
homolog of Xeroderma pigmentosum complementation group B 2
- Curated Summary
-
Encodes XPB2, a DNA repair protein and transcription factor. Arabidopsis thaliana has duplicated XPB gene (AtXPB1 and AtXPB2, with high similarity to each other). XPB proteins are involved in both DNA repair and transcription, they are component of the transcription factor IIH (TFIIH) and are responsible for DNA helicase activity during nucleotide (nt) excision repair (NER). Complementation assays in yeast rad25 mutant strains suggest the involvement of AtXPB2 in DNA repair. Although both genes are expressed in a constitutive manner during the plant life cycle, Northern blot analyses suggest that light modulates the expression level of both XPB copies.
Identifiers
| Identifier | Name |
|---|---|
| alias | XPB2 |
| alias | ATXPB2 |
| alias | ARABIDOPSIS HOMOLOG OF XERODERMA PIGMENTOSUM COMPLEMENTATION GROUP B 2 |
| alias | homolog of Xeroderma pigmentosum complementation group B 2 |
| uniprot | Q9FUG4 |
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Biological Process
| GO term | Evidence(s) | Provider | Description | Source |
|---|---|---|---|---|
| GO:0010224 | IEP | UniProt | response to UV-B | 1 2 3 4 |
| GO:0006289 | IEA | UniProt | nucleotide-excision repair | 1 2 3 |
| GO:0006355 | IEA | UniProt | regulation of transcription, DNA-dependent | 1 2 3 |
| GO:0006351 | IEA | UniProt | transcription, DNA-templated | 1 2 3 |
Molecular Function
| GO term | Evidence(s) | Provider | Description | Source |
|---|---|---|---|---|
| GO:0008026 | ISS | Gene Ontology | ATP-dependent helicase activity | 1 |
| GO:0004003 | IEA | UniProt | ATP-dependent DNA helicase activity | 1 2 3 |
| GO:0016787 | IEA | InterPro | hydrolase activity | |
| GO:0004386 | IEA | InterPro | helicase activity | |
| GO:0003676 | IEA | InterPro | nucleic acid binding | |
| GO:0003677 | IEA | UniProt | DNA binding | 1 2 3 |
| GO:0005524 | IEA | UniProt | ATP binding | 1 2 3 |
Cellular Component
| GO term | Evidence(s) | Provider | Description | Source |
|---|---|---|---|---|
| GO:0005634 | IEA, ISM | UniProt | nucleus | 1 2 3 4 |
Color Legend
| Experimental Evidence |
| Electronic Evidence |
| Computational Reviewed Evidence |
| Mapman id | Description |
|---|---|
| 28.2 | DNA.repair |
No SignalP domains detected for this gene.