Gene: AT5G18170 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G18170
Transcript Identifier
AT5G18170.1
Gene Type
Coding gene
Location
5 : 6006172-6008248 : positive

Family

Gene family
HOM03D001228
(125 genes in 30 species)
specific family
Subfamily
ORTHO03D000417
(90 genes in 30 species)
specific family
Duplication type
Block duplicate

Loading...please wait

Descriptions

Description
glutamate dehydrogenase 1
Curated Summary
Encodes the 43 kDa alpha-subunit of the glutamate dehydrogenase with a putative mitochondrial transit polypeptide and NAD(H)- and alpha-ketoglutarate-binding domains. Mitochondrial localization confirmed by subcellular fractionation. Combines in several ratios with GDH2 protein (GDH-beta) to form seven isoenzymes. Catalyzes the cleavage of glycine residues. May be involved in ammonia assimilation under conditions of inorganic nitrogen excess. The enzyme is almost exclusively found in the mitochondria of stem and leaf companion cells.
Show more...

Identifiers

Identifier Name
aliasglutamate dehydrogenase 1
aliasGDH1
uniprotQ43314

Toolbox

Explore

View

 

Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0046686IEP, RCA, UniProtresponse to cadmium ion1 2 3
GO:0009651IEPUniProtresponse to salt stress1 2
GO:0006807IMPUniProtnitrogen compound metabolic process1 2
GO:0009646IEPUniProtresponse to absence of light1 2
GO:0006520IEAUniProtcellular amino acid metabolic process1
GO:0055114IEAInterProoxidation-reduction process
GO:0009448ISOPLAZA Integrative Orthologygamma-aminobutyric acid metabolic processSL10G078550
GO:0051171ISOPLAZA Tree-based Orthologyregulation of nitrogen compound metabolic processAT3G03910

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016491ISS, IEAGene Ontologyoxidoreductase activity1
GO:0005524IDAUniProtATP binding1 2
GO:0005507IDAUniProtcopper ion binding1 2
GO:0008270IDAUniProtzinc ion binding1 2
GO:0050897IDAUniProtcobalt ion binding1 2
GO:0004353IDA, IMP, UniProtglutamate dehydrogenase [NAD(P)+] activity1 2 3

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005739IDA, ISM, UniProtmitochondrion1 2 3

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR006095Glutamate/phenylalanine/leucine/valine dehydrogenase
IPR006096Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal
IPR016040NAD(P)-binding domain
IPR006097Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain

Mapman id Description
12.3.1N-metabolism.N-degradation.glutamate dehydrogenase
No SignalP domains detected for this gene.