Gene: AT5G11670 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G11670
Transcript Identifier
AT5G11670.1
Gene Type
Coding gene
Location
5 : 3754456-3758040 : positive

Family

Gene family
HOM03D000487
(264 genes in 31 species)
specific family
Subfamily
ORTHO03D000208
(127 genes in 31 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
NADP-malic enzyme 2
Curated Summary
The malic enzyme (EC 1.1.1.40) encoded by AtNADP-ME2 is presumably a cytosolic enzyme involved in malate metabolism and possibly assisting the oxidative pentose phosphate pathway. AtNADP-ME2 counts for the major part of NADP-ME activity in mature tissues of Arabidopsis.
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Identifiers

Identifier Name
aliasNADP-malic enzyme 2
aliasNADP-ME2
aliasArabidopsis thaliana NADP-malic enzyme 2
aliasATNADP-ME2
uniprotQ9LYG3

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006108IDA, ISS, TASIEA, UniProtmalate metabolic process1 2 3 4 5 6 7 8 9
GO:0009051TASUniProtpentose-phosphate shunt, oxidative branch1 2 3 4 5 6 7
GO:0051260IDAUniProtprotein homooligomerization1 2 3 4 5 6 7
GO:0046686IEP, RCA, UniProtresponse to cadmium ion1 2 3 4 5 6 7 8
GO:0006094RCAGene Ontologygluconeogenesis1
GO:0006612RCAGene Ontologyprotein targeting to membrane1
GO:0006970RCAGene Ontologyresponse to osmotic stress1
GO:0007010RCAGene Ontologycytoskeleton organization1
GO:0009963RCAGene Ontologypositive regulation of flavonoid biosynthetic process1
GO:0010363RCAGene Ontologyregulation of plant-type hypersensitive response1
GO:0010498RCAGene Ontologyproteasomal protein catabolic process1
GO:0048767RCAGene Ontologyroot hair elongation1
GO:0055114IEAInterProoxidation-reduction process
GO:0043648IEAPLAZA Homologydicarboxylic acid metabolic processHOM03D000487
GO:0043436IEAPLAZA Homologyoxoacid metabolic processHOM03D000487
GO:0006082IEAPLAZA Homologyorganic acid metabolic processHOM03D000487
GO:0019752IEAPLAZA Homologycarboxylic acid metabolic processHOM03D000487

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004470ISS, IEAGene Ontologymalic enzyme activity1
GO:0016652ISSGene Ontologyoxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor1
GO:0004473IDAUniProtmalate dehydrogenase (decarboxylating) (NADP+) activity1 2 3 4 5 6 7
GO:0051287IEAUniProtNAD binding1 2 3 4 5 6
GO:0016491IEAInterProoxidoreductase activity
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5 6
GO:0016616IEAInterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0004471IEAUniProtmalate dehydrogenase (decarboxylating) (NAD+) activity1 2 3 4 5 6
GO:0050662IEAPLAZA Homologycoenzyme bindingHOM03D000487
GO:0048037IEAPLAZA Homologycofactor bindingHOM03D000487
GO:0016615IEAPLAZA Homologymalate dehydrogenase activityHOM03D000487
GO:0016614IEAPLAZA Homologyoxidoreductase activity, acting on CH-OH group of donorsHOM03D000487

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009507IDA, ISM, UniProtchloroplast1 2 3 4 5 6 7 8
GO:0005618IDAUniProtcell wall1 2 3 4 5 6 7
GO:0005774IDAUniProtvacuolar membrane1 2 3 4 5 6 7
GO:0005886IDAUniProtplasma membrane1 2 3 4 5 6 7
GO:0016020IDAGene Ontologymembrane1
GO:0048046IDAUniProtapoplast1 2 3 4 5 6 7
GO:0005829IDAUniProtcytosol1 2 3 4 5 6 7
GO:0009506IDAUniProtplasmodesma1 2 3 4 5 6 7

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001891Malic oxidoreductase
IPR015884Malic enzyme, conserved site
IPR012301Malic enzyme, N-terminal domain
IPR016040NAD(P)-binding domain
IPR012302Malic enzyme, NAD-binding

Mapman id Description
8.2.10TCA / org transformation.other organic acid transformatons.malic
No SignalP domains detected for this gene.