Gene: AT5G10380 (Arabidopsis thaliana)

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Gene Identifier
Transcript Identifier
Gene Type
Coding gene
5 : 3267819-3268724 : positive


Gene family
(2380 genes in 31 species)
specific family
(5 genes in 5 species)
specific family
Duplication type
Block duplicate

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RING/U-box superfamily protein
Curated Summary
Encodes a RING finger domain protein with E3 ligase activity that is localized to the lipid rafts of the plasma membrane. Expression is increased in response to fungal pathogen. May be involved in regulation of programmed cell death by facilitating degredation of regulation of PDC activators.
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Identifier Name





Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0010200IEPUniProtresponse to chitin1 2 3 4 5 6
GO:0002238IEPUniProtresponse to molecule of fungal origin1 2 3 4 5 6
GO:0009617IEP, RCA, UniProtresponse to bacterium1 2 3 4 5 6 7
GO:0012501ICUniProtprogrammed cell death1 2 3 4 5 6
GO:0016567IDAGene Ontologyprotein ubiquitination1
GO:0043068IMPUniProtpositive regulation of programmed cell death1 2 3 4 5 6
GO:0051865IDAUniProtprotein autoubiquitination1 2 3 4 5 6
GO:0000165RCAGene OntologyMAPK cascade1
GO:0006355RCAGene Ontologyregulation of transcription, DNA-dependent1
GO:0006612RCAGene Ontologyprotein targeting to membrane1
GO:0009627RCAGene Ontologysystemic acquired resistance1
GO:0009862RCAGene Ontologysystemic acquired resistance, salicylic acid mediated signaling pathway1
GO:0009867RCAGene Ontologyjasmonic acid mediated signaling pathway1
GO:0010310RCAGene Ontologyregulation of hydrogen peroxide metabolic process1
GO:0010363RCAGene Ontologyregulation of plant-type hypersensitive response1
GO:0019761RCAGene Ontologyglucosinolate biosynthetic process1
GO:0031348RCAGene Ontologynegative regulation of defense response1
GO:0034976RCAGene Ontologyresponse to endoplasmic reticulum stress1
GO:0035304RCAGene Ontologyregulation of protein dephosphorylation1
GO:0006915IEAUniProtapoptotic process1 2 3 4 5
GO:0006952IEAUniProtdefense response1 2 3 4 5

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008270IEA, ISSUniProtzinc ion binding1 2 3 4 5 6
GO:0004842IDAUniProtubiquitin-protein ligase activity1 2 3 4 5 6
GO:0005515IEAInterProprotein binding
GO:0043169IEAPLAZA Homologycation bindingHOM03D000017
GO:0005488IEAPLAZA HomologybindingHOM03D000017
GO:0043167IEAPLAZA Homologyion bindingHOM03D000017
GO:0046914IEAPLAZA Homologytransition metal ion bindingHOM03D000017
GO:0046872IEAPLAZA Homologymetal ion bindingHOM03D000017

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005576ISMGene Ontologyextracellular region1
GO:0005886IDAUniProtplasma membrane1 2 3 4 5 6
GO:0016021IEAUniProtintegral to membrane1 2 3 4 5

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type

Mapman id Description
No SignalP domains detected for this gene.