Gene: AT4G37930 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G37930
Transcript Identifier
AT4G37930.1
Gene Type
Coding gene
Location
4 : 17831891-17834742 : negative

Family

Gene family
HOM03D000445
(283 genes in 31 species)
specific family
Subfamily
ORTHO03D000453
(87 genes in 30 species)
specific family

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Descriptions

Description
serine transhydroxymethyltransferase 1
Curated Summary
Encodes a protein with mitochondrial serine hydroxymethyltransferase activity, which functions in the photorespiratory pathway, catalyzes the conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. Involved in controlling cell damage caused by abiotic stress, such as high light and salt and the hypersensitive defense response of plants.
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Identifiers

Identifier Name
aliasserine transhydroxymethyltransferase 1
aliasSHM1
aliasSERINE TRANSHYDROXYMETHYLTRANSFERASE
aliasSTM
aliasSERINE HYDROXYMETHYLTRANSFERASE 1
aliasSHMT1
uniprotQ9SZJ5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006544IDA, ISSIEA, UniProtglycine metabolic process1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0006563IDA, ISSIEA, UniProtL-serine metabolic process1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0019464IMPGene Ontologyglycine decarboxylation via glycine cleavage system1
GO:0007623IEPUniProtcircadian rhythm1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0009416IEPUniProtresponse to light stimulus1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0009626TASUniProtplant-type hypersensitive response1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0009853IMPUniProtphotorespiration1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0046686IEPUniProtresponse to cadmium ion1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0009409IEP, RCA, UniProtresponse to cold1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0009697RCAGene Ontologysalicylic acid biosynthetic process1
GO:0009814RCAGene Ontologydefense response, incompatible interaction1
GO:0019684RCAGene Ontologyphotosynthesis, light reaction1
GO:0042742RCAGene Ontologydefense response to bacterium1
GO:0035999IEAUniProttetrahydrofolate interconversion1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0009069IEAPLAZA Homologyserine family amino acid metabolic processHOM03D000445
GO:0044281IEAPLAZA Homologysmall molecule metabolic processHOM03D000445
GO:0043436IEAPLAZA Homologyoxoacid metabolic processHOM03D000445
GO:0006520IEAPLAZA Homologycellular amino acid metabolic processHOM03D000445
GO:1901564IEAPLAZA Homologyorganonitrogen compound metabolic processHOM03D000445
GO:1901605IEAPLAZA Homologyalpha-amino acid metabolic processHOM03D000445
GO:0006082IEAPLAZA Homologyorganic acid metabolic processHOM03D000445
GO:0019752IEAPLAZA Homologycarboxylic acid metabolic processHOM03D000445

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004372IDA, ISS, TASIEA, UniProtglycine hydroxymethyltransferase activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0008266IDAUniProtpoly(U) RNA binding1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0005515IPIGene Ontologyprotein binding1
GO:0030170IEAUniProtpyridoxal phosphate binding1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0003824IEAInterProcatalytic activity
GO:0048037IEAPLAZA Homologycofactor bindingHOM03D000445
GO:0016742IEAPLAZA Homologyhydroxymethyl-, formyl- and related transferase activityHOM03D000445
GO:0016741IEAPLAZA Homologytransferase activity, transferring one-carbon groupsHOM03D000445

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005739IDA, ISMGene Ontologymitochondrion1 2
GO:0005759ISSUniProtmitochondrial matrix1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0005634IDAUniProtnucleus1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0009507IDAGene Ontologychloroplast1
GO:0022626IDAUniProtcytosolic ribosome1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0010319IDAUniProtstromule1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0005886IDAUniProtplasma membrane1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0016020IDAGene Ontologymembrane1
GO:0048046IDAUniProtapoplast1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0009534IDAUniProtchloroplast thylakoid1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0009570IDAUniProtchloroplast stroma1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0005829IDAGene Ontologycytosol1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001085Serine hydroxymethyltransferase
IPR015422Pyridoxal phosphate-dependent transferase, major region, subdomain 2
IPR019798Serine hydroxymethyltransferase, pyridoxal phosphate binding site
IPR015424Pyridoxal phosphate-dependent transferase
IPR015421Pyridoxal phosphate-dependent transferase, major region, subdomain 1

Mapman id Description
25.1C1-metabolism.glycine hydroxymethyltransferase
No SignalP domains detected for this gene.