Gene: AT4G34460 (Arabidopsis thaliana)

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Gene Identifier
AT4G34460
Transcript Identifier
AT4G34460.1
Gene Type
Coding gene
Location
4 : 16477393-16479266 : negative

Family

Gene family
HOM03D001548
(104 genes in 31 species)
specific family
Subfamily
ORTHO03D003858
(37 genes in 29 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

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Descriptions

Description
GTP binding protein beta 1
Curated Summary
Encodes the heterotrimeric G-protein beta subunit and is involved in organ shape. A significant fraction of the protein is found in the ER. Mutants carrying null alleles express similar fruit phenotypes, as seen in er plants, but differ from er in that the stem is only slightly shorter than that in the wild type, the pedicel is slightly longer than that in the wild type, and the leaves are rounder than those in er mutants. Gene is expressed in all tissues examined, with highest expression level found in siliques. It is involved in resistance to Plectosphaerella cucumerina. The predicted protein has two DWD motifs. It can bind to DDB1a in Y2H assays and may be involved in the formation of a CUL4-based E3 ubiquitin ligase. It seems to be involved in the calcium-mediated response to extracellular ATP.
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Identifiers

Identifier Name
aliasGTP binding protein beta 1
aliasELK4
aliasERECTA-LIKE 4
aliasATAGB1
aliasAGB1
uniprotP49177

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009887IMPUniProtorgan morphogenesis1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0010154IMPUniProtfruit development1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0072593IMPUniProtreactive oxygen species metabolic process1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0050832IMP, RCAGene Ontologydefense response to fungus1 2
GO:0009867IMP, RCA, UniProtjasmonic acid mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0009788IMPUniProtnegative regulation of abscisic acid-activated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0009845IEP, IMP, UniProtseed germination1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0030968IMP, RCA, UniProtendoplasmic reticulum unfolded protein response1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0009723IMP, RCA, UniProtresponse to ethylene1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0048364IMPGene Ontologyroot development1
GO:0009817IMPUniProtdefense response to fungus, incompatible interaction1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0048527IMP, RCA, UniProtlateral root development1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0009991IMPUniProtresponse to extracellular stimulus1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0000165RCAGene OntologyMAPK cascade1
GO:0006355RCAGene Ontologyregulation of transcription, DNA-dependent1
GO:0006612RCAGene Ontologyprotein targeting to membrane1
GO:0007154RCAGene Ontologycell communication1
GO:0009409RCAGene Ontologyresponse to cold1
GO:0009617RCAGene Ontologyresponse to bacterium1
GO:0009737RCAGene Ontologyresponse to abscisic acid1
GO:0009738IEA, RCAUniProtabscisic acid-activated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0009862RCAGene Ontologysystemic acquired resistance, salicylic acid mediated signaling pathway1
GO:0009863RCAGene Ontologysalicylic acid mediated signaling pathway1
GO:0010200RCAGene Ontologyresponse to chitin1
GO:0010310RCAGene Ontologyregulation of hydrogen peroxide metabolic process1
GO:0010363RCAGene Ontologyregulation of plant-type hypersensitive response1
GO:0031348RCAGene Ontologynegative regulation of defense response1
GO:0035304RCAGene Ontologyregulation of protein dephosphorylation1
GO:0042744RCAGene Ontologyhydrogen peroxide catabolic process1
GO:0043069RCAGene Ontologynegative regulation of programmed cell death1
GO:0048193RCAGene OntologyGolgi vesicle transport1
GO:0051707RCAGene Ontologyresponse to other organism1
GO:2000280IGIUniProtregulation of root development1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0007186ISOPLAZA Integrative OrthologyG-protein coupled receptor signaling pathwayOS03G46650
GO:0006886IEAPLAZA Homologyintracellular protein transportHOM03D001548
GO:0016192IEAPLAZA Homologyvesicle-mediated transportHOM03D001548

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0000166ISSGene Ontologynucleotide binding1
GO:0005515IPI, IEAGene Ontologyprotein binding1
GO:0003924ISSUniProtGTPase activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0004871IEAUniProtsignal transducer activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0005198IEAPLAZA Homologystructural molecule activityHOM03D001548
GO:0005488IEAPLAZA HomologybindingHOM03D001548

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737IDA, ISMGene Ontologycytoplasm1 2
GO:0005834IDA, IPIISS, UniProtheterotrimeric G-protein complex1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0005886IDAGene Ontologyplasma membrane1
GO:0005783IDAUniProtendoplasmic reticulum1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0080008IPIUniProtCul4-RING ubiquitin ligase complex1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0030126IEAPLAZA HomologyCOPI vesicle coatHOM03D001548

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001632G-protein, beta subunit
IPR001680WD40 repeat
IPR019775WD40 repeat, conserved site
IPR017986WD40-repeat-containing domain
IPR020472G-protein beta WD-40 repeat
IPR015943WD40/YVTN repeat-like-containing domain

Mapman id Description
30.5signalling.G-proteins
No SignalP domains detected for this gene.