Gene: AT4G33240 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G33240
Transcript Identifier
AT4G33240.1
Gene Type
Coding gene
Location
4 : 16029504-16037278 : negative

Family

Gene family
HOM03D000867
(165 genes in 31 species)
specific family
Subfamily
ORTHO03D000138
(152 genes in 30 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
1-phosphatidylinositol-4-phosphate 5-kinases;zinc ion binding;1-phosphatidylinositol-3-phosphate 5-kinases
Curated Summary
Encodes a protein that is predicted to act as a 1-phosphatidylinositol-3-phosphate (PtdIns3P) 5-kinase based on its homology to Fab1 from yeast. It contains an FYVE domain required for binding to PtdIns3P-containing membranes in yeast, as well as a Cpn60_TCP1 homology domain plus a kinase domain. fab1a/fab1b pollen grains not viable and have defective vacuolar organization. FAB1A and FAB1B complement the enlarged vacuolar phenotype of the fission yeast ste12delta mutant.
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Identifiers

Identifier Name
aliasFAB1A
aliasFORMS APLOID AND BINUCLEATE CELLS 1A
uniprotQ0WUR5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0007033IGIUniProtvacuole organization1 2 3 4 5 6
GO:0009555IGIUniProtpollen development1 2 3 4 5 6
GO:0010256IGIUniProtendomembrane system organization1 2 3 4 5 6
GO:0009887RCAGene Ontologyorgan morphogenesis1
GO:0009888RCAGene Ontologytissue development1
GO:0010228RCAGene Ontologyvegetative to reproductive phase transition of meristem1
GO:0010638RCAGene Ontologypositive regulation of organelle organization1
GO:0016926RCAGene Ontologyprotein desumoylation1
GO:0033044RCAGene Ontologyregulation of chromosome organization1
GO:0050665RCAGene Ontologyhydrogen peroxide biosynthetic process1
GO:0046488IEAInterProphosphatidylinositol metabolic process
GO:0044267IEAUniProtcellular protein metabolic process1 2 3 4 5
GO:0006650IEAPLAZA Homologyglycerophospholipid metabolic processHOM03D000867
GO:0046486IEAPLAZA Homologyglycerolipid metabolic processHOM03D000867
GO:0006644IEAPLAZA Homologyphospholipid metabolic processHOM03D000867

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008270ISSGene Ontologyzinc ion binding1
GO:0016308ISSGene Ontology1-phosphatidylinositol-4-phosphate 5-kinase activity1
GO:0000285IGI, ISS, UniProt1-phosphatidylinositol-3-phosphate 5-kinase activity1 2 3 4 5 6 7
GO:0016307IEAInterProphosphatidylinositol phosphate kinase activity
GO:0005524IEAUniProtATP binding1 2 3 4 5
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005768IDAUniProtendosome1 2 3 4 5 6
GO:0010008IEAUniProtendosome membrane1 2 3 4 5

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR027483Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
IPR000306FYVE zinc finger
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR016034Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
IPR011011Zinc finger, FYVE/PHD-type
IPR027409GroEL-like apical domain
IPR002498Phosphatidylinositol-4-phosphate 5-kinase, core
IPR017455Zinc finger, FYVE-related
IPR002423Chaperonin Cpn60/TCP-1
IPR027484Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain

Mapman id Description
30.4.1signalling.phosphinositides.phosphatidylinositol-4-phosphate 5-kinase
No SignalP domains detected for this gene.