Gene: AT4G24220 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G24220
Transcript Identifier
AT4G24220.1
Gene Type
Coding gene
Location
4 : 12565219-12566474 : positive

Family

Gene family
HOM03D001013
(147 genes in 29 species)
specific family
Subfamily
ORTHO03D000639
(73 genes in 29 species)
specific family

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Descriptions

Description
NAD(P)-binding Rossmann-fold superfamily protein
Curated Summary
encodes a progesterone-5beta-reductase-like protein. It has enone reductase activity against a wide range of substrates, including 3-oxo-Δ-4,5-steroids in vitro. The in vivo substrates and product of this enzyme have not yet been elucidated but it is likely to participate in steroid metabolism. The protein contains a mammalian death domain involved in programmed cell death. The gene is expressed in the vascular system and mutants carrying a dominant mutation in the gene have defective vascular patterning. VEP1 gene expression is induced specifically by wounding.
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Identifiers

Identifier Name
aliasVEIN PATTERNING 1
aliasΔ4,5-steroid-5[beta]-reductase
alias5[beta]-StR
aliasAWI31
aliasVEP1
uniprotQ9STX2

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009611IEPUniProtresponse to wounding1 2 3 4 5 6 7 8
GO:0010051IMPUniProtxylem and phloem pattern formation1 2 3 4 5 6 7 8
GO:0008202IDAUniProtsteroid metabolic process1 2 3 4 5 6 7 8

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0035671IDAUniProtenone reductase activity1 2 3 4 5 6 7 8
GO:0047787IEAUniProtdelta4-3-oxosteroid 5beta-reductase activity1 2 3 4 5 6 7

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005829IDAUniProtcytosol1 2 3 4 5 6 7 8

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR016040NAD(P)-binding domain

Mapman id Description
33.99development.unspecified
No SignalP domains detected for this gene.