Gene: AT4G23100 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G23100
Transcript Identifier
AT4G23100.1
Gene Type
Coding gene
Location
4 : 12103458-12106751 : negative

Family

Gene family
HOM03D002981
(61 genes in 31 species)
specific family
Subfamily
ORTHO03D001635
(48 genes in 31 species)
specific family

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Descriptions

Description
glutamate-cysteine ligase
Curated Summary
Encodes the enzyme glutamate-cysteine ligase catalyzing the first, and rate-limiting, step of glutathione biosynthesis. Required for cell proliferation at the root tip. Involved in susceptibility to the bacterial pathogen Pseudomonas syringae. Mutants are phytoalexin defective.
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Identifiers

Identifier Name
aliasAtGSH1
aliasCADMIUM SENSITIVE 2
aliasROOT MERISTEMLESS 1
aliasglutamate-cysteine ligase
aliasPAD2
aliasPHYTOALEXIN DEFICIENT 2
aliasATECS1
aliasGSH1
aliasGSHA
aliasRML1
aliasCAD2
uniprotP46309

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009908IMPUniProtflower development1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0006750IDA, IMP, TASIEA, UniProtglutathione biosynthetic process1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
GO:0009408IMPUniProtresponse to heat1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0009753IEPUniProtresponse to jasmonic acid1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0010193IEP, RCA, UniProtresponse to ozone1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
GO:0046686IMP, IEP, RCA, UniProtresponse to cadmium ion1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
GO:0050832IMPUniProtdefense response to fungus1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0002213IMPUniProtdefense response to insect1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0019761IMPUniProtglucosinolate biosynthetic process1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0042742IMPGene Ontologydefense response to bacterium1
GO:0052544IMPUniProtdefense response by callose deposition in cell wall1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0006007RCAGene Ontologyglucose catabolic process1
GO:0006094RCAGene Ontologygluconeogenesis1
GO:0006096RCAGene Ontologyglycolysis1
GO:0009651RCAGene Ontologyresponse to salt stress1
GO:0019344RCAGene Ontologycysteine biosynthetic process1
GO:0030244RCAGene Ontologycellulose biosynthetic process1
GO:0009700IMPUniProtindole phytoalexin biosynthetic process1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0009816IMPUniProtdefense response to bacterium, incompatible interaction1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0042398IEAInterProcellular modified amino acid biosynthetic process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004357IDA, IMPIEA, UniProtglutamate-cysteine ligase activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009507IDA, ISMGene Ontologychloroplast1 2
GO:0009570IDAUniProtchloroplast stroma1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
GO:0009536IDAGene Ontologyplastid1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011556Glutamate--cysteine ligase, plant
IPR006336Glutamate--cysteine ligase, GCS2

Mapman id Description
21.2.2redox.ascorbate and glutathione.glutathione
No SignalP domains detected for this gene.