Gene: AT3G48780 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G48780
Transcript Identifier
AT3G48780.1
Gene Type
Coding gene
Location
3 : 18089346-18092276 : positive

Family

Gene family
HOM03D002277
(77 genes in 30 species)
specific family
Subfamily
ORTHO03D001252
(54 genes in 30 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

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Descriptions

Description
serine palmitoyltransferase 1
Curated Summary
Encodes one of the two LCB2 subunits (LCB2a and LCB2b) of serine palmitoyltransferase, an enzyme involved in sphingolipid biosynthesis. LCB2a and LCB2b are functional redundant. Double mutants are gametophytic lethal.
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Identifiers

Identifier Name
aliasSERINE PALMITOYLTRANSFERASE 1
aliasATSPT1
aliasserine palmitoyltransferase 1
aliasSPT1
uniprotQ9M304

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0030148IMP, ISS, UniProtsphingolipid biosynthetic process1 2 3 4 5
GO:0009555IMPUniProtpollen development1 2 3 4
GO:0009640IMPUniProtphotomorphogenesis1 2 3 4
GO:0009058IEAInterProbiosynthetic process
GO:0008152IEAInterPrometabolic process
GO:0043067ISOPLAZA Tree-based Orthologyregulation of programmed cell deathAT5G23670
GO:0046512ISOPLAZA Tree-based Orthologysphingosine biosynthetic processAT5G23670

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004758IGI, ISS, UniProtserine C-palmitoyltransferase activity1 2 3 4 5
GO:0030170IEAUniProtpyridoxal phosphate binding1 2 3
GO:0003824IEAInterProcatalytic activity
GO:0016740IEAInterProtransferase activity
GO:0005515ISOPLAZA Tree-based Orthologyprotein bindingAT5G23670

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009507ISMGene Ontologychloroplast1
GO:0005789IEAUniProtendoplasmic reticulum membrane1 2 3
GO:0016021IEAUniProtintegral to membrane1 2 3
GO:0005773ISOPLAZA Tree-based OrthologyvacuoleAT5G23670
GO:0016020ISOPLAZA Tree-based OrthologymembraneAT5G23670
GO:0005783ISOPLAZA Tree-based Orthologyendoplasmic reticulumAT5G23670

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004839Aminotransferase, class I/classII
IPR015422Pyridoxal phosphate-dependent transferase, major region, subdomain 2
IPR015421Pyridoxal phosphate-dependent transferase, major region, subdomain 1
IPR015424Pyridoxal phosphate-dependent transferase
IPR001917Aminotransferase, class-II, pyridoxal-phosphate binding site

Mapman id Description
11.8.1.2lipid metabolism.exotics (steroids, squalene etc).sphingolipids.serine C-palmitoyltransferase
No SignalP domains detected for this gene.