Gene: AT3G48430 (Arabidopsis thaliana)

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Gene Identifier
AT3G48430
Transcript Identifier
AT3G48430.1
Gene Type
Coding gene
Location
3 : 17935609-17940456 : positive

Family

Gene family
HOM03D000357
(342 genes in 31 species)
specific family
Subfamily
ORTHO03D006637
(32 genes in 22 species)
specific family

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Descriptions

Description
relative of early flowering 6
Curated Summary
Relative of Early Flowering 6 (REF6) encodes a Jumonji N/C and zinc finger domain-containing protein that acts as a positive regulator of flowering in an FLC-dependent pathway. REF6 mutants have hyperacetylation of histone H4 at the FLC locus. REF6 interacts with BES1 in a Y2H assay and in vitro. REF6 may play a role in brassinoteroid signaling by affecting histone methylation in the promoters of BR-responsive genes. It is most closely related to the JHDM3 subfamily of JmjN/C proteins.
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Identifiers

Identifier Name
aliasREF6
aliasrelative of early flowering 6
aliasJumonji domain-containing protein 12
aliasJMJ12
uniprotQ9STM3

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0010228IMPUniProtvegetative to reproductive phase transition of meristem1 2 3 4 5 6 7 8
GO:0035067IMPUniProtnegative regulation of histone acetylation1 2 3 4 5 6 7 8
GO:0009741IMPUniProtresponse to brassinosteroid1 2 3 4 5 6 7 8
GO:0009826IMPUniProtunidimensional cell growth1 2 3 4 5 6 7 8
GO:0033169IMPUniProthistone H3-K9 demethylation1 2 3 4 5 6 7 8
GO:0048366IMPUniProtleaf development1 2 3 4 5 6 7 8
GO:0006355IEAUniProtregulation of transcription, DNA-dependent1 2 3 4 5 6 7
GO:0006351IEAUniProttranscription, DNA-templated1 2 3 4 5 6 7

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003700ISSGene Ontologysequence-specific DNA binding transcription factor activity1
GO:0005515IEAInterProprotein binding
GO:0003676IEAUniProtnucleic acid binding1 2 3 4 5 6 7
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5 6 7
GO:0051213IEAUniProtdioxygenase activity1 2 3 4 5 6 7

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISM, UniProtnucleus1 2 3 4 5 6 7 8 9

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR007087Zinc finger, C2H2
IPR015880Zinc finger, C2H2-like
IPR003349Transcription factor jumonji, JmjN
IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
IPR003347JmjC domain

Mapman id Description
27.3.57RNA.regulation of transcription.JUMONJI family
No SignalP domains detected for this gene.
DatabaseType
PlnTFDBC2H2
PlantTFDBC2H2