Gene: AT3G47450 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G47450
Transcript Identifier
AT3G47450.1
Gene Type
Coding gene
Location
3 : 17483195-17486249 : negative

Family

Gene family
HOM03D006367
(34 genes in 31 species)
specific family

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Descriptions

Description
P-loop containing nucleoside triphosphate hydrolases superfamily protein
Curated Summary
Encodes a protein with similarity to the bacterial YqeH GTPase required for proper ribosome assembly. In Arabidopsis, mutant analyses show that this protein regulates growth and hormonal signaling in plants. It also attenuates oxidative stress and reactive oxygen species (ROS). It also seems to be involved in regulating leaf senescence and cell death. This gene product is also involved in nitric oxide biosynthesis in response to ABA but not exogenous H2O2. This protein also appears to be required for proper plastid biogenesis. Levels of several plastid-localized proteins, including RBCL, ClpP1, and the MEP biosynthesis enzymes DXS and DXR are altered in rif1-1 mutants. This protein was originally characterized as a mitrochondrial-localized nitric oxide synthase, but, the synthase activity was later disproven. In addition, new studies with GFP fusion proteins and chloroplast import assays suggest that this protein is found in chloroplasts.
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Identifiers

Identifier Name
aliasNOS1
aliasNO ASSOCIATED 1
aliasNOA1
aliasRIF1
aliasNITRIC OXIDE SYNTHASE 1
aliasRESISTANT TO INHIBITION WITH FOSMIDOMYCIN 1
aliasATNOA1
aliasATNOS1
uniprotQ66GP9

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006809IDAGene Ontologynitric oxide biosynthetic process1
GO:0006979IDAGene Ontologyresponse to oxidative stress1
GO:0009651IMPUniProtresponse to salt stress1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0009657IMPGene Ontologyplastid organization1
GO:0010027IMP, RCAGene Ontologythylakoid membrane organization1 2
GO:0010322IMPGene Ontologyregulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway1
GO:0048366IMPGene Ontologyleaf development1
GO:0051246IMPGene Ontologyregulation of protein metabolic process1
GO:0010193IMPGene Ontologyresponse to ozone1
GO:0006364RCAGene OntologyrRNA processing1
GO:0006399RCAGene OntologytRNA metabolic process1
GO:0006655RCAGene Ontologyphosphatidylglycerol biosynthetic process1
GO:0006897RCAGene Ontologyendocytosis1
GO:0009658RCAGene Ontologychloroplast organization1
GO:0009793RCAGene Ontologyembryo development ending in seed dormancy1
GO:0009902RCAGene Ontologychloroplast relocation1
GO:0009965RCAGene Ontologyleaf morphogenesis1
GO:0010228RCAGene Ontologyvegetative to reproductive phase transition of meristem1
GO:0016226RCAGene Ontologyiron-sulfur cluster assembly1
GO:0019288RCAGene Ontologyisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway1
GO:0030154RCAGene Ontologycell differentiation1
GO:0034660RCAGene OntologyncRNA metabolic process1
GO:0042793RCAGene Ontologytranscription from plastid promoter1
GO:0045893RCAGene Ontologypositive regulation of transcription, DNA-dependent1
GO:0048481RCAGene Ontologyovule development1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005525IEA, IBAUniProtGTP binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0003924IDAGene OntologyGTPase activity1
GO:0004517IEA, IDAUniProtnitric-oxide synthase activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0016787IEAUniProthydrolase activity1 2 3 4 5 6 7 8 9 10 11 12 13 14

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009507IEA, IDA, ISMUniProtchloroplast1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0005739IEA, IDAUniProtmitochondrion1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006073GTP binding domain
IPR027417P-loop containing nucleoside triphosphate hydrolase

Mapman id Description
35.2not assigned.unknown
No SignalP domains detected for this gene.