Gene: AT3G47390 (Arabidopsis thaliana)

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Gene Identifier
AT3G47390
Transcript Identifier
AT3G47390.1
Gene Type
Coding gene
Location
3 : 17462094-17464655 : positive

Family

Gene family
HOM03D004126
(46 genes in 29 species)
specific family
Subfamily
ORTHO03D003695
(37 genes in 29 species)
specific family

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Descriptions

Description
cytidine/deoxycytidylate deaminase family protein
Curated Summary
Encodes a protein that is believed to function as a pyrimidine reductase involved in riboflavin and FAD biosynthesis. phs1 was identified as a photosensitive mutant that shows reduced growth, chloroplast developmental abnormalities, reduced chlorophyll levels, increased oxidative stress, reduced NADPH/NADP+ ratios, reduced photosystem I electron transport, and reduced photosynthetic protein levels under high light conditions. Many of these abnormal phenotypes likely arise from the reduction in the levels of FAD in the phs1 mutant.
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Identifiers

Identifier Name
aliaspyrimidine reductase
aliasPyrR
aliasPHOTOSENSITIVE 1
aliasPHS1
uniprotQ9STY4

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009644IMPUniProtresponse to high light intensity1 2 3 4
GO:0009658IMPUniProtchloroplast organization1 2 3 4
GO:0046443IMPUniProtFAD metabolic process1 2 3 4
GO:0055114IEAInterProoxidation-reduction process
GO:0009231IEAUniProtriboflavin biosynthetic process1 2 3
GO:0042727IEAPLAZA Homologyflavin-containing compound biosynthetic processHOM03D004126
GO:0006771IEAPLAZA Homologyriboflavin metabolic processHOM03D004126

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008270IEA, ISSUniProtzinc ion binding1 2 3 4
GO:0016787ISS, IEAGene Ontologyhydrolase activity1
GO:0008703IDA, NASIEA, UniProt5-amino-6-(5-phosphoribosylamino)uracil reductase activity1 2 3 4 5
GO:0050661IEAUniProtNADP binding1 2 3
GO:0008835IEAUniProtdiaminohydroxyphosphoribosylaminopyrimidine deaminase activity1 2 3
GO:0003824IEAInterProcatalytic activity

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009507IDA, ISM, UniProtchloroplast1 2 3 4 5

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR012816Conserved hypothetical protein CHP02464
IPR004794Riboflavin biosynthesis protein RibD
IPR011549Riboflavin-specific deaminase, C-terminal
IPR024072Dihydrofolate reductase-like domain
IPR002734Bacterial bifunctional deaminase-reductase, C-terminal
IPR002125CMP/dCMP deaminase, zinc-binding
IPR016193Cytidine deaminase-like

Mapman id Description
23.5.3nucleotide metabolism.deoxynucleotide metabolism.cytosine deaminase
No SignalP domains detected for this gene.