Gene: AT3G19150 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G19150
Transcript Identifier
AT3G19150.1
Gene Type
Coding gene
Location
3 : 6616628-6617655 : negative

Family

Gene family
HOM03D000965
(154 genes in 28 species)
specific family
Subfamily
ORTHO03D027492
(5 genes in 5 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
KIP-related protein 6
Curated Summary
Kip-related protein (KRP) gene, encodes CDK (cyclin-dependent kinase) inhibitor (CKI), negative regulator of cell division. Binds to D type cyclins. A member of seven KRP genes found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization. KRP6 appears to be targeted for degradation by RHF1a and RHF2a to allow mitotic divisions during gametogenesis. In addition, KRP6 transcript levels rise prior to and drop following the meitotic divisions of gametogenesis. Elevated levels of KRP6 negatively affect plant development and fertility.
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Identifiers

Identifier Name
aliasAtKRP6
aliasICK4
aliasKIP-related protein 6
aliasACK1
aliasKRP6
aliasARABIDOPSIS CDK INHIBITOR 1
uniprotQ0WNX9

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0042023IMPGene OntologyDNA endoreduplication1 AGRICOLA_IND:IND23305253
GO:0045736IDA, TAS, UniProtnegative regulation of cyclin-dependent protein serine/threonine kinase activity1 AGRICOLA_IND:IND233052532 3 4 5 6 7 8 9 10 11
GO:0007050IEAUniProtcell cycle arrest1 2 3 4 5 6 7 8 9
GO:0048519IEAPLAZA Homologynegative regulation of biological processHOM03D000965
GO:0051726IEAPLAZA Homologyregulation of cell cycleHOM03D000965
GO:0048523IEAPLAZA Homologynegative regulation of cellular processHOM03D000965
GO:0022402IEAPLAZA Homologycell cycle processHOM03D000965
GO:0045786IEAPLAZA Homologynegative regulation of cell cycleHOM03D000965
GO:0007049IEAPLAZA Homologycell cycleHOM03D000965

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004861IEA, TASUniProtcyclin-dependent protein serine/threonine kinase inhibitor activity1 AGRICOLA_IND:IND233052532 3 4 5 6 7 8 9 10
GO:0030332IPIGene Ontologycyclin binding1 AGRICOLA_IND:IND23305253
GO:0005515IPIGene Ontologyprotein binding1
GO:0019207IEAPLAZA Homologykinase regulator activityHOM03D000965
GO:0019887IEAPLAZA Homologyprotein kinase regulator activityHOM03D000965
GO:0016538IEAPLAZA Homologycyclin-dependent protein serine/threonine kinase regulator activityHOM03D000965
GO:0004857IEAPLAZA Homologyenzyme inhibitor activityHOM03D000965
GO:0019210IEAPLAZA Homologykinase inhibitor activityHOM03D000965
GO:0030291IEAPLAZA Homologyprotein serine/threonine kinase inhibitor activityHOM03D000965
GO:0004860IEAPLAZA Homologyprotein kinase inhibitor activityHOM03D000965

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISM, IEAGene Ontologynucleus1
GO:0001673IDAUniProtmale germ cell nucleus1 2 3 4 5 6 7 8 9 10
GO:0005654IEAUniProtnucleoplasm1 2 3 4 5 6 7 8 9

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003175Cyclin-dependent kinase inhibitor

Mapman id Description
31.3cell.cycle
No SignalP domains detected for this gene.