Gene: AT3G08730 (Arabidopsis thaliana)

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Gene Identifier
AT3G08730
Transcript Identifier
AT3G08730.1
Gene Type
Coding gene
Location
3 : 2651581-2653363 : negative

Family

Gene family
HOM03D000076
(1177 genes in 31 species)
specific family
Subfamily
ORTHO03D000661
(72 genes in 30 species)
specific family
Duplication type
Tandem duplicate

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Descriptions

Description
protein-serine kinase 1
Curated Summary
Encodes a protein-serine kinase that phosphorylates ribosomal protein in vitro. Activation of AtS6k is regulated by 1-naphthylacetic acid and kinetin, at least in part, via a lipid kinase-dependent pathway. Involved in translational up-regulation of ribosomal proteins. Phosphorylated by PDK1. Interacts with RAPTOR1, which in turn interacts with TOR. SPK6 activity is affected by osmotic stress, and plants overexpressing S6k1 are hypersensitive to osmotic stress. The gene is expressed in all tissues examined, with highest expression level detected in metabolically active tissues.
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Identifiers

Identifier Name
aliasPK6
aliasATS6K1
aliasARABIDOPSIS THALIANA PROTEIN-SERINE KINASE 6
aliasS6K1
aliasP70 RIBOSOMAL S6 KINASE
aliasARABIDOPSIS THALIANA PROTEIN-SERINE KINASE 1
aliasROTEIN-SERINE KINASE 6
aliasATPK6
aliasATPK1
aliasPK1
aliasprotein-serine kinase 1
uniprotP42818

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006970IDA, IMPGene Ontologyresponse to osmotic stress1 2
GO:0045727TAS, RCAUniProtpositive regulation of translation1 2 3 4 5 6 7 8 9 10
GO:0009409IEPUniProtresponse to cold1 2 3 4 5 6 7 8 9
GO:0009651IEPUniProtresponse to salt stress1 2 3 4 5 6 7 8 9
GO:0006468IDA, IEAGene Ontologyprotein phosphorylation1
GO:0009408ISOPLAZA Tree-based Orthologyresponse to heatAT3G08720
GO:0044260IEAPLAZA Homologycellular macromolecule metabolic processHOM03D000076
GO:0006796IEAPLAZA Homologyphosphate-containing compound metabolic processHOM03D000076
GO:0006793IEAPLAZA Homologyphosphorus metabolic processHOM03D000076
GO:0043170IEAPLAZA Homologymacromolecule metabolic processHOM03D000076
GO:0044237IEAPLAZA Homologycellular metabolic processHOM03D000076
GO:0044238IEAPLAZA Homologyprimary metabolic processHOM03D000076
GO:0009987IEAPLAZA Homologycellular processHOM03D000076
GO:0016310IEAPLAZA HomologyphosphorylationHOM03D000076
GO:0008152IEAPLAZA Homologymetabolic processHOM03D000076
GO:0043412IEAPLAZA Homologymacromolecule modificationHOM03D000076
GO:0071704IEAPLAZA Homologyorganic substance metabolic processHOM03D000076
GO:0044267IEAPLAZA Homologycellular protein metabolic processHOM03D000076
GO:0019538IEAPLAZA Homologyprotein metabolic processHOM03D000076
GO:0036211IEAPLAZA Homologyprotein modification processHOM03D000076
GO:0006464IEAPLAZA Homologycellular protein modification processHOM03D000076

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016301IDA, ISSGene Ontologykinase activity1 2
GO:0005515IPIGene Ontologyprotein binding1
GO:0004672ISS, IEAGene Ontologyprotein kinase activity1
GO:0004674IDA, IEA, UniProtprotein serine/threonine kinase activity1 2 3 4 5 6 7 8 9
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7 8
GO:0016772IEAInterProtransferase activity, transferring phosphorus-containing groups
GO:0032555IEAPLAZA Homologypurine ribonucleotide bindingHOM03D000076
GO:0043168IEAPLAZA Homologyanion bindingHOM03D000076
GO:0032553IEAPLAZA Homologyribonucleotide bindingHOM03D000076
GO:0043167IEAPLAZA Homologyion bindingHOM03D000076
GO:0035639IEAPLAZA Homologypurine ribonucleoside triphosphate bindingHOM03D000076
GO:0097367IEAPLAZA Homologycarbohydrate derivative bindingHOM03D000076
GO:0003824IEAPLAZA Homologycatalytic activityHOM03D000076
GO:0032559IEAPLAZA Homologyadenyl ribonucleotide bindingHOM03D000076
GO:1901265IEAPLAZA Homologynucleoside phosphate bindingHOM03D000076
GO:0000166IEAPLAZA Homologynucleotide bindingHOM03D000076
GO:0001882IEAPLAZA Homologynucleoside bindingHOM03D000076
GO:0030554IEAPLAZA Homologyadenyl nucleotide bindingHOM03D000076
GO:0016773IEAPLAZA Homologyphosphotransferase activity, alcohol group as acceptorHOM03D000076
GO:0017076IEAPLAZA Homologypurine nucleotide bindingHOM03D000076
GO:0097159IEAPLAZA Homologyorganic cyclic compound bindingHOM03D000076
GO:0036094IEAPLAZA Homologysmall molecule bindingHOM03D000076
GO:0032549IEAPLAZA Homologyribonucleoside bindingHOM03D000076
GO:0005488IEAPLAZA HomologybindingHOM03D000076
GO:1901363IEAPLAZA Homologyheterocyclic compound bindingHOM03D000076
GO:0001883IEAPLAZA Homologypurine nucleoside bindingHOM03D000076
GO:0032550IEAPLAZA Homologypurine ribonucleoside bindingHOM03D000076
GO:0016740IEAPLAZA Homologytransferase activityHOM03D000076

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737IDAUniProtcytoplasm1 2 3 4 5 6 7 8 9
GO:0005634ISOPLAZA Tree-based OrthologynucleusAT3G08720

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR017892Protein kinase, C-terminal
IPR002290Serine/threonine- / dual specificity protein kinase, catalytic domain
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site
IPR000961AGC-kinase, C-terminal
IPR008271Serine/threonine-protein kinase, active site

Mapman id Description
29.2.2protein.synthesis.ribosome biogenesis
No SignalP domains detected for this gene.