Gene: AT3G07370 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G07370
Transcript Identifier
AT3G07370.1
Gene Type
Coding gene
Location
3 : 2358323-2360301 : negative

Family

Gene family
HOM03D003914
(48 genes in 30 species)
specific family
Subfamily
ORTHO03D003729
(37 genes in 30 species)
specific family

Loading...please wait

Descriptions

Description
carboxyl terminus of HSC70-interacting protein
Curated Summary
Encodes AtCHIP, a new class of E3 ubiquitin ligases with three tetratricopeptide repeats and a U-box domain, structurally similar to the animal CHIP proteins. Plays an important role in plant cellular metabolism under temperature stress conditions. Functions as an E3 ubiquitin ligase of protein phosphatase 2A subunits and alters plant response to abscisic acid treatment. Belongs to one of the 36 carboxylate clamp (CC)-tetratricopeptide repeat (TPR) proteins (Prasad 2010, Pubmed ID: 20856808) with potential to interact with Hsp90/Hsp70 as co-chaperones.
Show more...

Identifiers

Identifier Name
aliascarboxyl terminus of HSC70-interacting protein
aliasCHIP
aliasCARBOXYL TERMINUS OF HSC70-INTERACTING PROTEIN
aliasATCHIP
uniprotQ9SRS9

Toolbox

Explore

View

 

Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009266IMP, IEPUniProtresponse to temperature stimulus1 2 3 4 5 6 7 8 9
GO:0016567IDA, IEAGene Ontologyprotein ubiquitination1
GO:0009651IEPUniProtresponse to salt stress1 2 3 4 5 6 7 8
GO:0009737IMPUniProtresponse to abscisic acid1 2 3 4 5 6 7 8
GO:0007165RCAGene Ontologysignal transduction1
GO:0009408RCAGene Ontologyresponse to heat1
GO:0009414RCAGene Ontologyresponse to water deprivation1
GO:0009610RCAGene Ontologyresponse to symbiotic fungus1
GO:0009611RCAGene Ontologyresponse to wounding1
GO:0009723RCAGene Ontologyresponse to ethylene1
GO:0009733RCAGene Ontologyresponse to auxin1
GO:0009738RCAGene Ontologyabscisic acid-activated signaling pathway1
GO:0009753RCAGene Ontologyresponse to jasmonic acid1
GO:0042538RCAGene Ontologyhyperosmotic salinity response1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004842IDA, IEA, UniProtubiquitin-protein ligase activity1 2 3 4 5 6 7 8
GO:0051087IPIGene Ontologychaperone binding1
GO:0005515IEAInterProprotein binding

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1
GO:0000151IEAUniProtubiquitin ligase complex1 2 3 4 5 6 7

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR013105Tetratricopeptide TPR2
IPR019734Tetratricopeptide repeat
IPR003613U box domain
IPR011990Tetratricopeptide-like helical
IPR013026Tetratricopeptide repeat-containing domain

Mapman id Description
29.5.11.4.2protein.degradation.ubiquitin.E3.RING
No SignalP domains detected for this gene.