Gene: AT2G39200 (Arabidopsis thaliana)

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Gene Identifier
AT2G39200
Transcript Identifier
AT2G39200.1
Gene Type
Coding gene
Location
2 : 16356255-16359797 : negative

Family

Gene family
HOM03D000181
(566 genes in 31 species)
specific family
Subfamily
ORTHO03D000563
(77 genes in 25 species)
specific family

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Descriptions

Description
Seven transmembrane MLO family protein
Curated Summary
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO6 belongs to the clade IV, with AtMLO2, AtMLO3 and AtMLO12. The gene is expressed during early seedling growth, in root tips and cotyledon vascular system, in floral organs (anthers and stigma), and in fruit abscission zone, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
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Identifiers

Identifier Name
aliasMLO12
aliasMILDEW RESISTANCE LOCUS O 12
aliasATMLO12
uniprotO80961

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006952IMP, ISS, IEAGene Ontologydefense response1 2
GO:0008219ISSGene Ontologycell death1
GO:0009817IMPUniProtdefense response to fungus, incompatible interaction1 2 3
GO:0010150IMPUniProtleaf senescence1 2 3
GO:0002679RCAGene Ontologyrespiratory burst involved in defense response1
GO:0006857RCAGene Ontologyoligopeptide transport1
GO:0006865RCAGene Ontologyamino acid transport1
GO:0009407RCAGene Ontologytoxin catabolic process1
GO:0010200RCAGene Ontologyresponse to chitin1
GO:0010583RCAGene Ontologyresponse to cyclopentenone1
GO:0015824RCAGene Ontologyproline transport1
GO:0031348ISOPLAZA Tree-based Orthologynegative regulation of defense responseAT1G11310
GO:0006950IEAPLAZA Homologyresponse to stressHOM03D000181
GO:0050896IEAPLAZA Homologyresponse to stimulusHOM03D000181

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005516ISSGene Ontologycalmodulin binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886IDA, ISSTAS, UniProtplasma membrane1 2 3 4 5
GO:0016021IEAUniProtintegral to membrane1 2
GO:0005794ISOPLAZA Tree-based OrthologyGolgi apparatusAT1G11310
GO:0009506ISOPLAZA Tree-based OrthologyplasmodesmaAT1G11310
GO:0016020IEAPLAZA HomologymembraneHOM03D000181
GO:0031224IEAPLAZA Homologyintrinsic to membraneHOM03D000181
GO:0044425IEAPLAZA Homologymembrane partHOM03D000181

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004326Mlo-related protein

Mapman id Description
20.1.3.1stress.biotic.signalling.MLO-like
No SignalP domains detected for this gene.