Gene: AT2G38700 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT2G38700
Transcript Identifier
AT2G38700.1
Gene Type
Coding gene
Location
2 : 16180918-16183785 : negative

Family

Gene family
HOM03D003412
(53 genes in 29 species)
specific family
Subfamily
ORTHO03D018919
(7 genes in 7 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
mevalonate diphosphate decarboxylase 1
Curated Summary
Encodes mevalonate diphosphate decarboxylase, the enzyme that catalyzes the synthesis of isopentenyl diphosphate, used in sterol and isoprenoid biosynthesis. The protein appears to form a homodimeric complex. Incidentally, it was shown that the Arabidopsis MVD protein could also interact with its yeast homolog to form a heterodimer.
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Identifiers

Identifier Name
aliasmevalonate diphosphate decarboxylase 1
aliasATMVD1
aliasMVD1

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0008610IGIGene Ontologylipid biosynthetic process1
GO:0019287TASGene Ontologyisopentenyl diphosphate biosynthetic process, mevalonate pathway1
GO:0006084RCAGene Ontologyacetyl-CoA metabolic process1
GO:0006085RCAGene Ontologyacetyl-CoA biosynthetic process1
GO:0016126RCAGene Ontologysterol biosynthetic process1
GO:0016132RCAGene Ontologybrassinosteroid biosynthetic process1
GO:0019745RCAGene Ontologypentacyclic triterpenoid biosynthetic process1
GO:0008299IEAInterProisoprenoid biosynthetic process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004163IGI, IEAGene Ontologydiphosphomevalonate decarboxylase activity1
GO:0042803IPIGene Ontologyprotein homodimerization activity1
GO:0005524IEAInterProATP binding

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005829IDAGene Ontologycytosol1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006204GHMP kinase N-terminal domain
IPR005935Diphosphomevalonate decarboxylase
IPR014721Ribosomal protein S5 domain 2-type fold, subgroup
IPR020568Ribosomal protein S5 domain 2-type fold

Mapman id Description
16.1.2.6secondary metabolism.isoprenoids.mevalonate pathway.mevalonate diphosphate decarboxylase
No SignalP domains detected for this gene.