Gene: AT2G32040 (Arabidopsis thaliana)

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Gene Identifier
AT2G32040
Transcript Identifier
AT2G32040.1
Gene Type
Coding gene
Location
2 : 13635116-13637592 : positive

Family

Gene family
HOM03D000607
(224 genes in 31 species)
specific family
Subfamily
ORTHO03D001899
(45 genes in 31 species)
specific family

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Descriptions

Description
Major facilitator superfamily protein
Curated Summary
The At2g32040 gene product has been demonstrated to mediate folate monoglutamate transport involved in tetrahydrofolate biosynthesis. It also mediates transport of antifolates, such as methotrexate and aminopterin. The gene is expressed in both chloroplast and non-green plastids.
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Identifiers

Identifier Name
uniprotQ9SKZ5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006810ISSGene Ontologytransport1
GO:0051958IDAGene Ontologymethotrexate transport1
GO:0009987IEAPLAZA Homologycellular processHOM03D000607

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005215ISSGene Ontologytransporter activity1
GO:0008517IDAGene Ontologyfolic acid transporter activity1
GO:0015231IDAUniProt5-formyltetrahydrofolate transporter activity1 2 3 4 5
GO:0015350IDAUniProtmethotrexate transporter activity1 2 3 4 5

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009507ISMGene Ontologychloroplast1
GO:0016020ISSGene Ontologymembrane1
GO:0009941IDAUniProtchloroplast envelope1 2 3 4 5
GO:0031969IEAUniProtchloroplast membrane1 2 3 4
GO:0016021IEAUniProtintegral to membrane1 2 3 4

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004324Biopterin transport-related protein BT1
IPR016196Major facilitator superfamily domain, general substrate transporter

Mapman id Description
34.99transport.misc
No SignalP domains detected for this gene.