Gene: AT2G26300 (Arabidopsis thaliana)

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Gene Identifier
AT2G26300
Transcript Identifier
AT2G26300.1
Gene Type
Coding gene
Location
2 : 11198087-11200822 : positive

Family

Gene family
HOM03D000757
(185 genes in 29 species)
specific family
Subfamily
ORTHO03D005266
(34 genes in 28 species)
specific family

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Descriptions

Description
G protein alpha subunit 1
Curated Summary
Encodes an alpha subunit of a heterotrimeric GTP-binding protein. The active GTP-bound form of GPA1 binds to the GTG1 and GTG2 abscisic acid (ABA) receptors and appears to affect their GTPase and GTP-binding activity, and hence, ABA binding abilities. GPA1 is a positive regulator in ABA-mediated inhibition of stomatal opening. Plants with recessive mutant alleles have complex phenotypes including: reduced brassinolide response, reduced cell divisions, round leaves, short hypocotyls. It is likely to be involved in the signaling events that trigger unfolded protein response-associated cell death. GPA1 is also involved in sugar signaling.
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Identifiers

Identifier Name
aliasATGPA1
aliasG PROTEIN ALPHA SUBUNIT 1
aliasARABIDOPSIS THALIANA G PROTEIN ALPHA SUBUNIT 1
aliasG protein alpha subunit 1
aliasGP ALPHA 1
aliasGPA1
uniprotP18064

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0007186ISS, IEAGene OntologyG-protein coupled receptor signaling pathway1
GO:0007188IBAUniProtadenylate cyclase-modulating G-protein coupled receptor signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0009738IMP, TAS, UniProtabscisic acid-activated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0009740IMPUniProtgibberellic acid mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0009845IEP, IMP, UniProtseed germination1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0001789IMPUniProtG-protein coupled receptor signaling pathway, coupled to S1P second messenger1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0042127IMPUniProtregulation of cell proliferation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0008219IMP, RCA, UniProtcell death1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0010119IMP, TAS, UniProtregulation of stomatal movement1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0072593IMPUniProtreactive oxygen species metabolic process1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0006571IMPUniProttyrosine biosynthetic process1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0009094IMPUniProtL-phenylalanine biosynthetic process1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0010244IMPUniProtresponse to low fluence blue light stimulus by blue low-fluence system1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0009788IMPUniProtnegative regulation of abscisic acid-activated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0071215IEPGene Ontologycellular response to abscisic acid stimulus1
GO:0009789IMPUniProtpositive regulation of abscisic acid-activated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0009785IMPUniProtblue light signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0009749IGI, RCA, UniProtresponse to glucose1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0010027IMPUniProtthylakoid membrane organization1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0000278RCAGene Ontologymitotic cell cycle1
GO:0000303RCAGene Ontologyresponse to superoxide1
GO:0006396RCAGene OntologyRNA processing1
GO:0007165RCA, IEAGene Ontologysignal transduction1
GO:0009744RCAGene Ontologyresponse to sucrose1
GO:0009750RCAGene Ontologyresponse to fructose1
GO:0009755RCAGene Ontologyhormone-mediated signaling pathway1
GO:0009863RCAGene Ontologysalicylic acid mediated signaling pathway1
GO:0009873RCAGene Ontologyethylene mediated signaling pathway1
GO:0006184IEAInterProGTP catabolic process
GO:0007166IEAPLAZA Homologycell surface receptor signaling pathwayHOM03D000757

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0001664IBAUniProtG-protein coupled receptor binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0004871IBA, ISSIEA, UniProtsignal transducer activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0031683IBA, IEA, UniProtG-protein beta/gamma-subunit complex binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0016247IMPUniProtchannel regulator activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0005515IPIGene Ontologyprotein binding1
GO:0003924IDA, IEA, UniProtGTPase activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0005525IDA, IEA, UniProtGTP binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0005095IDAUniProtGTPase inhibitor activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0051020IPIGene OntologyGTPase binding1
GO:0019001IEAInterProguanyl nucleotide binding
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0060089IEAPLAZA Homologymolecular transducer activityHOM03D000757
GO:0032403IEAPLAZA Homologyprotein complex bindingHOM03D000757

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1
GO:0031234IBAGene Ontologyextrinsic to cytoplasmic side of plasma membrane1
GO:0005834IDA, IPITAS, UniProtheterotrimeric G-protein complex1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
GO:0005886IDAGene Ontologyplasma membrane1
GO:0009506IDAUniProtplasmodesma1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0005789IDAUniProtendoplasmic reticulum membrane1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002976Plant G-protein, alpha subunit
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR011025G protein alpha subunit, helical insertion
IPR001019Guanine nucleotide binding protein (G-protein), alpha subunit

Mapman id Description
30.5signalling.G-proteins
No SignalP domains detected for this gene.