Gene: AT2G19900 (Arabidopsis thaliana)

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Gene Identifier
AT2G19900
Transcript Identifier
AT2G19900.1
Gene Type
Coding gene
Location
2 : 8592106-8595403 : negative

Family

Gene family
HOM03D000487
(264 genes in 31 species)
specific family
Subfamily
ORTHO03D000208
(127 genes in 31 species)
specific family

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Descriptions

Description
NADP-malic enzyme 1
Curated Summary
The malic enzyme (EC 1.1.1.40) encoded by AtNADP-ME1 is expressed in response to developmental and cell-specific signals. The enzyme is active in vitro and appears to function as a homohexamer or homooctamer. It is believed to be a cytosolic protein.
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Identifiers

Identifier Name
aliasArabidopsis thaliana NADP-malic enzyme 1
aliasNADP-malic enzyme 1
aliasNADP-ME1
aliasATNADP-ME1
uniprotO82191

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006108IDA, ISSIEA, UniProtmalate metabolic process1 2 3 4 5
GO:0051260IDAUniProtprotein homooligomerization1 2 3 4
GO:0006094RCAGene Ontologygluconeogenesis1
GO:0007010RCAGene Ontologycytoskeleton organization1
GO:0010498RCAGene Ontologyproteasomal protein catabolic process1
GO:0055114IEAInterProoxidation-reduction process
GO:0043648IEAPLAZA Homologydicarboxylic acid metabolic processHOM03D000487
GO:0043436IEAPLAZA Homologyoxoacid metabolic processHOM03D000487
GO:0006082IEAPLAZA Homologyorganic acid metabolic processHOM03D000487
GO:0019752IEAPLAZA Homologycarboxylic acid metabolic processHOM03D000487

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004470ISS, IEAGene Ontologymalic enzyme activity1
GO:0016652ISSGene Ontologyoxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor1
GO:0004473IDAUniProtmalate dehydrogenase (decarboxylating) (NADP+) activity1 2 3 4
GO:0051287IEAUniProtNAD binding1 2 3
GO:0016491IEAInterProoxidoreductase activity
GO:0046872IEAUniProtmetal ion binding1 2 3
GO:0016616IEAInterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0004471IEAUniProtmalate dehydrogenase (decarboxylating) (NAD+) activity1 2 3
GO:0050662IEAPLAZA Homologycoenzyme bindingHOM03D000487
GO:0048037IEAPLAZA Homologycofactor bindingHOM03D000487
GO:0016615IEAPLAZA Homologymalate dehydrogenase activityHOM03D000487
GO:0016614IEAPLAZA Homologyoxidoreductase activity, acting on CH-OH group of donorsHOM03D000487

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1
GO:0005829NASUniProtcytosol1 2 3 4

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001891Malic oxidoreductase
IPR012301Malic enzyme, N-terminal domain
IPR012302Malic enzyme, NAD-binding
IPR016040NAD(P)-binding domain
IPR015884Malic enzyme, conserved site

Mapman id Description
8.2.10TCA / org transformation.other organic acid transformatons.malic
No SignalP domains detected for this gene.