PLAZA 3.0 Dicots gene overview : AT2G19110

Gene: AT2G19110 (Arabidopsis thaliana)

Overview

Gene Identifier: AT2G19110
Transcript Identifier: AT2G19110.1
Gene Type: Coding gene
Location: 2 : 8279478-8286255 : positive

Family

Gene family: HOM03D000216
(475 genes in 31 species)
specific family
Subfamily: ORTHO03D000839
(65 genes in 30 species)
specific family
Duplication type: Block duplicate

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Descriptions

Description: heavy metal atpase 4

Curated Summary: Encodes a protein with similarity to Zn ATPase. Can rescue Zn deficiency in yeast and Cd resistance, suggesting a role in Zn and Cd transport.

Identifiers

Identifier	Name
alias	HMA4
alias	ARABIDOPSIS HEAVY METAL ATPASE 4
alias	ATHMA4
alias	heavy metal atpase 4
uniprot	O64474

Toolbox

Explore

...the colinearity of this gene with other genomes.
...the local gene organization for homologous genes.
...the phylogenetic tree of the homologous gene family.
...the orthologs using the Integrative Orthology Viewer.
...the conserved binding sites (upstream/downstream,intron)

View

Biological Process

GO term	Evidence(s)	Provider	Description	Source
GO:0055069	IGI	UniProt	zinc ion homeostasis	1 2 3 4
GO:0010038	IMP	Gene Ontology	response to metal ion	1
GO:0010043	IMP	UniProt	response to zinc ion	1 2 3 4
GO:0030001	IMP, IEA	Gene Ontology	metal ion transport	1
GO:0032025	IMP	UniProt	response to cobalt ion	1 2 3 4
GO:0046686	IMP	UniProt	response to cadmium ion	1 2 3 4
GO:0006829	IMP	Gene Ontology	zinc ion transport	1
GO:0015691	IMP	Gene Ontology	cadmium ion transport	1
GO:0000041	RCA	Gene Ontology	transition metal ion transport	1
GO:0006812	IEA	InterPro	cation transport
GO:0044765	IEA	PLAZA Homology	single-organism transport	HOM03D000216
GO:0051234	IEA	PLAZA Homology	establishment of localization	HOM03D000216
GO:0006810	IEA	PLAZA Homology	transport	HOM03D000216
GO:0006811	IEA	PLAZA Homology	ion transport	HOM03D000216
GO:0051179	IEA	PLAZA Homology	localization	HOM03D000216

Molecular Function

GO term	Evidence(s)	Provider	Description	Source
GO:0015434	ISS	Gene Ontology	cadmium-transporting ATPase activity	1
GO:0005385	IGI	UniProt	zinc ion transmembrane transporter activity	1 2 3 4
GO:0015086	IGI	UniProt	cadmium ion transmembrane transporter activity	1 2 3 4
GO:0005515	IPI	Gene Ontology	protein binding	1
GO:0019829	IEA	InterPro	cation-transporting ATPase activity
GO:0000166	IEA	InterPro	nucleotide binding
GO:0046872	IEA	UniProt	metal ion binding	1 2 3
GO:0005524	IEA	UniProt	ATP binding	1 2 3
GO:0008551	IEA	UniProt	cadmium-exporting ATPase activity	1 2 3
GO:0016463	IEA	UniProt	zinc-exporting ATPase activity	1 2 3
GO:0005215	IEA	PLAZA Homology	transporter activity	HOM03D000216
GO:0016817	IEA	PLAZA Homology	hydrolase activity, acting on acid anhydrides	HOM03D000216
GO:0042623	IEA	PLAZA Homology	ATPase activity, coupled	HOM03D000216
GO:0015075	IEA	PLAZA Homology	ion transmembrane transporter activity	HOM03D000216
GO:0008324	IEA	PLAZA Homology	cation transmembrane transporter activity	HOM03D000216
GO:0042626	IEA	PLAZA Homology	ATPase activity, coupled to transmembrane movement of substances	HOM03D000216
GO:0042625	IEA	PLAZA Homology	ATPase activity, coupled to transmembrane movement of ions	HOM03D000216
GO:0022804	IEA	PLAZA Homology	active transmembrane transporter activity	HOM03D000216
GO:0016818	IEA	PLAZA Homology	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	HOM03D000216
GO:1901265	IEA	PLAZA Homology	nucleoside phosphate binding	HOM03D000216
GO:0016462	IEA	PLAZA Homology	pyrophosphatase activity	HOM03D000216
GO:0022891	IEA	PLAZA Homology	substrate-specific transmembrane transporter activity	HOM03D000216
GO:0022892	IEA	PLAZA Homology	substrate-specific transporter activity	HOM03D000216
GO:0016820	IEA	PLAZA Homology	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	HOM03D000216
GO:0016887	IEA	PLAZA Homology	ATPase activity	HOM03D000216
GO:0017111	IEA	PLAZA Homology	nucleoside-triphosphatase activity	HOM03D000216
GO:0015399	IEA	PLAZA Homology	primary active transmembrane transporter activity	HOM03D000216
GO:0015405	IEA	PLAZA Homology	P-P-bond-hydrolysis-driven transmembrane transporter activity	HOM03D000216
GO:0022857	IEA	PLAZA Homology	transmembrane transporter activity	HOM03D000216
GO:0043492	IEA	PLAZA Homology	ATPase activity, coupled to movement of substances	HOM03D000216

Cellular Component

GO term	Evidence(s)	Provider	Description	Source
GO:0005886	IDA, ISMTAS,	UniProt	plasma membrane	1 2 3 4 5 6
GO:0009506	IDA	UniProt	plasmodesma	1 2 3 4
GO:0016021	IEA	UniProt	integral to membrane	1 2 3
GO:0005774	ISO	PLAZA Tree-based Orthology	vacuolar membrane	AT4G30120
GO:0031224	IEA	PLAZA Homology	intrinsic to membrane	HOM03D000216
GO:0044425	IEA	PLAZA Homology	membrane part	HOM03D000216

Color Legend

Experimental Evidence

Electronic Evidence

Computational Reviewed Evidence

InterPro	Description
IPR027256	Cation-transporting P-type ATPase, subfamily IB
IPR023214	HAD-like domain
IPR001757	Cation-transporting P-type ATPase
IPR006121	Heavy metal-associated domain, HMA
IPR018303	P-type ATPase, phosphorylation site
IPR027265	Divalent cation-transporting P-type ATPase
IPR008250	P-type ATPase, A domain
IPR023299	P-type ATPase, cytoplasmic domain N

Mapman id	Description
34.12	transport.metal

No SignalP domains detected for this gene.