Gene: AT2G19110 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT2G19110
Transcript Identifier
AT2G19110.1
Gene Type
Coding gene
Location
2 : 8279478-8286255 : positive

Family

Gene family
HOM03D000216
(475 genes in 31 species)
specific family
Subfamily
ORTHO03D000839
(65 genes in 30 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
heavy metal atpase 4
Curated Summary
Encodes a protein with similarity to Zn ATPase. Can rescue Zn deficiency in yeast and Cd resistance, suggesting a role in Zn and Cd transport.
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Identifiers

Identifier Name
aliasHMA4
aliasARABIDOPSIS HEAVY METAL ATPASE 4
aliasATHMA4
aliasheavy metal atpase 4
uniprotO64474

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0055069IGIUniProtzinc ion homeostasis1 2 3 4
GO:0010038IMPGene Ontologyresponse to metal ion1
GO:0010043IMPUniProtresponse to zinc ion1 2 3 4
GO:0030001IMP, IEAGene Ontologymetal ion transport1
GO:0032025IMPUniProtresponse to cobalt ion1 2 3 4
GO:0046686IMPUniProtresponse to cadmium ion1 2 3 4
GO:0006829IMPGene Ontologyzinc ion transport1
GO:0015691IMPGene Ontologycadmium ion transport1
GO:0000041RCAGene Ontologytransition metal ion transport1
GO:0006812IEAInterProcation transport
GO:0044765IEAPLAZA Homologysingle-organism transportHOM03D000216
GO:0051234IEAPLAZA Homologyestablishment of localizationHOM03D000216
GO:0006810IEAPLAZA HomologytransportHOM03D000216
GO:0006811IEAPLAZA Homologyion transportHOM03D000216
GO:0051179IEAPLAZA HomologylocalizationHOM03D000216

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0015434ISSGene Ontologycadmium-transporting ATPase activity1
GO:0005385IGIUniProtzinc ion transmembrane transporter activity1 2 3 4
GO:0015086IGIUniProtcadmium ion transmembrane transporter activity1 2 3 4
GO:0005515IPIGene Ontologyprotein binding1
GO:0019829IEAInterProcation-transporting ATPase activity
GO:0000166IEAInterPronucleotide binding
GO:0046872IEAUniProtmetal ion binding1 2 3
GO:0005524IEAUniProtATP binding1 2 3
GO:0008551IEAUniProtcadmium-exporting ATPase activity1 2 3
GO:0016463IEAUniProtzinc-exporting ATPase activity1 2 3
GO:0005215IEAPLAZA Homologytransporter activityHOM03D000216
GO:0016817IEAPLAZA Homologyhydrolase activity, acting on acid anhydridesHOM03D000216
GO:0042623IEAPLAZA HomologyATPase activity, coupledHOM03D000216
GO:0015075IEAPLAZA Homologyion transmembrane transporter activityHOM03D000216
GO:0008324IEAPLAZA Homologycation transmembrane transporter activityHOM03D000216
GO:0042626IEAPLAZA HomologyATPase activity, coupled to transmembrane movement of substancesHOM03D000216
GO:0042625IEAPLAZA HomologyATPase activity, coupled to transmembrane movement of ionsHOM03D000216
GO:0022804IEAPLAZA Homologyactive transmembrane transporter activityHOM03D000216
GO:0016818IEAPLAZA Homologyhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesHOM03D000216
GO:1901265IEAPLAZA Homologynucleoside phosphate bindingHOM03D000216
GO:0016462IEAPLAZA Homologypyrophosphatase activityHOM03D000216
GO:0022891IEAPLAZA Homologysubstrate-specific transmembrane transporter activityHOM03D000216
GO:0022892IEAPLAZA Homologysubstrate-specific transporter activityHOM03D000216
GO:0016820IEAPLAZA Homologyhydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesHOM03D000216
GO:0016887IEAPLAZA HomologyATPase activityHOM03D000216
GO:0017111IEAPLAZA Homologynucleoside-triphosphatase activityHOM03D000216
GO:0015399IEAPLAZA Homologyprimary active transmembrane transporter activityHOM03D000216
GO:0015405IEAPLAZA HomologyP-P-bond-hydrolysis-driven transmembrane transporter activityHOM03D000216
GO:0022857IEAPLAZA Homologytransmembrane transporter activityHOM03D000216
GO:0043492IEAPLAZA HomologyATPase activity, coupled to movement of substancesHOM03D000216

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886IDA, ISMTAS, UniProtplasma membrane1 2 3 4 5 6
GO:0009506IDAUniProtplasmodesma1 2 3 4
GO:0016021IEAUniProtintegral to membrane1 2 3
GO:0005774ISOPLAZA Tree-based Orthologyvacuolar membraneAT4G30120
GO:0031224IEAPLAZA Homologyintrinsic to membraneHOM03D000216
GO:0044425IEAPLAZA Homologymembrane partHOM03D000216

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR027256Cation-transporting P-type ATPase, subfamily IB
IPR023214HAD-like domain
IPR001757Cation-transporting P-type ATPase
IPR006121Heavy metal-associated domain, HMA
IPR018303P-type ATPase, phosphorylation site
IPR027265Divalent cation-transporting P-type ATPase
IPR008250P-type ATPase, A domain
IPR023299P-type ATPase, cytoplasmic domain N

Mapman id Description
34.12transport.metal
No SignalP domains detected for this gene.