Gene: AT1G69770 (Arabidopsis thaliana)

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Gene Identifier
Transcript Identifier
Gene Type
Coding gene
1 : 26248496-26253519 : negative


Gene family
(203 genes in 30 species)
specific family
(43 genes in 26 species)
specific family

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chromomethylase 3
Curated Summary
Encodes a chromomethylase involved in methylating cytosine residues at non-CG sites. Involved in preferentially methylating transposon-related sequences, reducing their mobility. CMT3 interacts with an Arabidopsis homologue of HP1 (heterochromatin protein 1), which in turn interacts with methylated histones. Involved in gene silencing.
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Identifier Name
aliaschromomethylase 3





Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006342IGI, RCA, UniProtchromatin silencing1 2 3 4 5 6 7 8 9
GO:0010425IMPUniProtDNA methylation on cytosine within a CNG sequence1 2 3 4 5 6 7 8
GO:0045814IGIGene Ontologynegative regulation of gene expression, epigenetic1
GO:0006306IMP, RCA, IEAGene OntologyDNA methylation1 2
GO:0010069IMPUniProtzygote asymmetric cytokinesis in embryo sac1 2 3 4 5 6 7 8
GO:0051567IGI, RCA, UniProthistone H3-K9 methylation1 2 3 4 5 6 7 8 9
GO:0006260RCAGene OntologyDNA replication1
GO:0006261RCAGene OntologyDNA-dependent DNA replication1
GO:0006270RCAGene OntologyDNA replication initiation1
GO:0006275RCAGene Ontologyregulation of DNA replication1
GO:0006346RCAGene Ontologymethylation-dependent chromatin silencing1
GO:0008283RCAGene Ontologycell proliferation1
GO:0009909RCAGene Ontologyregulation of flower development1
GO:0016458RCAGene Ontologygene silencing1
GO:0016572RCAGene Ontologyhistone phosphorylation1
GO:0031047RCAGene Ontologygene silencing by RNA1
GO:0031048RCAGene Ontologychromatin silencing by small RNA1
GO:0034968RCAGene Ontologyhistone lysine methylation1
GO:0051726RCAGene Ontologyregulation of cell cycle1
GO:0006351IEAUniProttranscription, DNA-templated1 2 3 4 5 6 7
GO:0006304IEAPLAZA HomologyDNA modificationHOM03D000685
GO:0032259IEAPLAZA HomologymethylationHOM03D000685
GO:0006305IEAPLAZA HomologyDNA alkylationHOM03D000685
GO:0043414IEAPLAZA Homologymacromolecule methylationHOM03D000685
GO:0044728IEAPLAZA HomologyDNA methylation or demethylationHOM03D000685
GO:0040029IEAPLAZA Homologyregulation of gene expression, epigeneticHOM03D000685

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003886IMPUniProtDNA (cytosine-5-)-methyltransferase activity1 2 3 4 5 6 7 8
GO:0008168IEAInterPromethyltransferase activity
GO:0003677IEAUniProtDNA binding1 2 3 4 5 6 7

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IEA, ISMUniProtnucleus1 2 3 4 5 6 7 8

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001525C-5 cytosine methyltransferase
IPR000953Chromo domain/shadow
IPR018117DNA methylase, C-5 cytosine-specific, active site
IPR023779Chromo domain, conserved site
IPR001025Bromo adjacent homology (BAH) domain
IPR016197Chromo domain-like
IPR025821DNA (cytosine-5-)-methyltransferase, plant
IPR023780Chromo domain

Mapman id Description
27.3.46RNA.regulation of transcription.DNA methyltransferases
No SignalP domains detected for this gene.