Gene: AT1G67070 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G67070
Transcript Identifier
AT1G67070.1
Gene Type
Coding gene
Location
1 : 25042324-25044412 : positive

Family

Gene family
HOM03D002446
(73 genes in 30 species)
specific family
Subfamily
ORTHO03D001563
(49 genes in 30 species)
specific family

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Descriptions

Description
Mannose-6-phosphate isomerase, type I
Curated Summary
Encodes a protein with phosphomannose isomerase activity that is involved in synthesis of ascorbic acid. Expression is induced after 24 hours of dark treatment, in senescing leaves and treatment with exogenous photosynthesis inhibitor. Induction of gene expression was suppressed in excised leaves supplied with sugar. The authors suggest that the gene's expression pattern is responding to the level of sugar in the cell.
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Identifiers

Identifier Name
aliasDIN9
aliasPHOSPHOMANNOSE ISOMERASE 2
aliasDARK INDUCIBLE 9
aliasPMI2
uniprotQ9FZH5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0005975ISS, IEAGene Ontologycarbohydrate metabolic process1
GO:0009744IEPUniProtresponse to sucrose1 2 3 4 5 6
GO:0009646IEPUniProtresponse to absence of light1 2 3 4 5 6
GO:0010043IEPUniProtresponse to zinc ion1 2 3 4 5 6
GO:0019853IMPUniProtL-ascorbic acid biosynthetic process1 2 3 4 5 6
GO:0033591IEPUniProtresponse to L-ascorbic acid1 2 3 4 5 6
GO:0046680IEPUniProtresponse to DDT1 2 3 4 5 6
GO:0046686IEPUniProtresponse to cadmium ion1 2 3 4 5 6
GO:0009298IEAUniProtGDP-mannose biosynthetic process1 2 3 4 5
GO:0032025ISOPLAZA Tree-based Orthologyresponse to cobalt ionAT3G02570
GO:0009793ISOPLAZA Tree-based Orthologyembryo development ending in seed dormancyAT3G02570

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004476IDA, ISSIEA, UniProtmannose-6-phosphate isomerase activity1 2 3 4 5 6 7
GO:0008270IEAUniProtzinc ion binding1 2 3 4 5

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR016305Mannose-6-phosphate isomerase
IPR001250Mannose-6-phosphate isomerase, type I
IPR014710RmlC-like jelly roll fold
IPR018050Phosphomannose isomerase, type I, conserved site
IPR011051RmlC-like cupin domain

Mapman id Description
10.1.20cell wall.precursor synthesis.phosphomannose isomerase
No SignalP domains detected for this gene.