Gene: AT1G66050 (Arabidopsis thaliana)

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Gene Identifier
AT1G66050
Transcript Identifier
AT1G66050.1
Gene Type
Coding gene
Location
1 : 24589534-24592616 : positive

Family

Gene family
HOM03D001750
(94 genes in 30 species)
specific family
Subfamily
ORTHO03D000897
(63 genes in 28 species)
specific family
Duplication type
Tandem duplicate

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Descriptions

Description
Zinc finger (C3HC4-type RING finger) family protein
Curated Summary
Encodes a protein that is similar to VIM1 but is not involved in cytosine methylation. This protein has an N-terminal PHD domain and two RING domains surrounding an SRA domain. ORTH5/VIM2 has E3 ubiquitin ligase activity in vitro.
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Identifiers

Identifier Name
aliasVIM2
aliasVARIANT IN METHYLATION 2
aliasORTH5
aliasORTHRUS 5
uniprotQ680I0

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0032776IMPGene OntologyDNA methylation on cytosine1
GO:0016567IDAGene Ontologyprotein ubiquitination1
GO:0090309IMPUniProtpositive regulation of methylation-dependent chromatin silencing1 2 3 4 5 6
GO:0016568IEAUniProtchromatin modification1 2 3 4 5
GO:0010424ISOPLAZA Integrative OrthologyDNA methylation on cytosine within a CG sequenceAT5G39550 AT1G57820
GO:0010228ISOPLAZA Integrative Orthologyvegetative to reproductive phase transition of meristemAT5G39550
GO:0051301ISOPLAZA Tree-based Orthologycell divisionAT1G57820
GO:0031508ISOPLAZA Tree-based Orthologycentromeric heterochromatin assemblyAT1G57820

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008270IEA, ISSUniProtzinc ion binding1 2 3 4 5 6
GO:0004842IDAUniProtubiquitin-protein ligase activity1 2 3 4 5 6
GO:0005515IEAInterProprotein binding
GO:0042393ISS, IEAUniProthistone binding1 2 3 4 5
GO:0046872IEAInterPrometal ion binding
GO:0008327ISSUniProtmethyl-CpG binding1 2 3 4 5
GO:0010428ISSUniProtmethyl-CpNpG binding1 2 3 4 5
GO:0010429ISSUniProtmethyl-CpNpN binding1 2 3 4 5
GO:0010385ISOPLAZA Tree-based Orthologydouble-stranded methylated DNA bindingAT1G57820
GO:0003682ISOPLAZA Tree-based Orthologychromatin bindingAT1G57820

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISM, UniProtnucleus1 2 3 4 5 6 7
GO:0005737ISOPLAZA Tree-based OrthologycytoplasmAT4G08590
GO:0010369ISOPLAZA Tree-based OrthologychromocenterAT1G57820

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003105SRA-YDG
IPR001841Zinc finger, RING-type
IPR001965Zinc finger, PHD-type
IPR017907Zinc finger, RING-type, conserved site
IPR018957Zinc finger, C3HC4 RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR015947PUA-like domain
IPR011011Zinc finger, FYVE/PHD-type
IPR019786Zinc finger, PHD-type, conserved site

Mapman id Description
29.5.11.4.2protein.degradation.ubiquitin.E3.RING
No SignalP domains detected for this gene.