Gene: AT1G58290 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G58290
Transcript Identifier
AT1G58290.1
Gene Type
Coding gene
Location
1 : 21624028-21626051 : negative

Family

Gene family
HOM03D002178
(79 genes in 31 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
Glutamyl-tRNA reductase family protein
Curated Summary
Encodes a protein with glutamyl-tRNA reductase (GluTR) activity, catalyzing the NADPH-dependent reduction of Glu-tRNA(Glu) to glutamate 1-semialdehyde (GSA) with the release of free tRNA(Glu). It is involved in the early steps of chlorophyll biosynthesis.
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Identifiers

Identifier Name
aliasAtHEMA1
aliasArabidopsis thaliana hemA 1
aliasHEMA1
uniprotP42804

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006783IMP, RCA, UniProtheme biosynthetic process1 2 3 4 5 6 7 8 9 10
GO:0015995IMPUniProtchlorophyll biosynthetic process1 2 3 4 5 6 7 8 9
GO:0000302RCAGene Ontologyresponse to reactive oxygen species1
GO:0010039RCAGene Ontologyresponse to iron ion1
GO:0055072RCAGene Ontologyiron ion homeostasis1
GO:0006779TASGene Ontologyporphyrin-containing compound biosynthetic process1
GO:0009416IEPGene Ontologyresponse to light stimulus1
GO:0033014IEAInterProtetrapyrrole biosynthetic process
GO:0055114IEAInterProoxidation-reduction process
GO:0006782IEAUniProtprotoporphyrinogen IX biosynthetic process1 2 3 4 5 6 7 8
GO:0006979ISOPLAZA Tree-based Orthologyresponse to oxidative stressAT1G09940

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008883TAS, IGI, IEA, UniProtglutamyl-tRNA reductase activity1 2 3 4 5 6 7 8 9 10
GO:0005515IPIGene Ontologyprotein binding1
GO:0050661IEAUniProtNADP binding1 2 3 4 5 6 7 8

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009507IDA, ISMTAS, UniProtchloroplast1 2 3 4 5 6 7 8 9 10 11
GO:0031969IEAUniProtchloroplast membrane1 2 3 4 5 6 7 8

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000343Tetrapyrrole biosynthesis, glutamyl-tRNA reductase
IPR015896Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain
IPR015895Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal
IPR018214Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, conserved site
IPR016040NAD(P)-binding domain
IPR006151Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase

Mapman id Description
19.2tetrapyrrole synthesis.glu-tRNA reductase
No SignalP domains detected for this gene.